Malaria remains a major cause of morbidity and mortality in the tropics, with Plasmodium
falciparum responsible for the majority of the disease burden and P. vivax being the …

In the past decade, there have been remarkable advances in proteomic technologies. Mass
spectrometry has emerged as the preferred method for in-depth characterization of the …

Commitment to and completion of sexual development are essential for malaria parasites
(protists of the genus Plasmodium) to be transmitted through mosquitoes. The molecular …

Abstract PlasmoDB (http://PlasmoDB. org) is a functional genomic database for Plasmodium
spp. that provides a resource for data analysis and visualization in a gene-by-gene or …

Sexual differentiation of malaria parasites into gametocytes in the vertebrate host and
subsequent gamete fertilization in mosquitoes is essential for the spreading of the disease …

Male and female gametocytes are the components of the malaria parasite life cycle which
are taken up from an infected host bloodstream by mosquitoes and thus mediate disease …

Translational repression of messenger RNAs (mRNAs) plays an important role in sexual
differentiation and gametogenesis in multicellular eukaryotes. Translational repression and …

Plasmodium sporozoites are transmitted from infected mosquitoes to mammals, and must
navigate the host skin and vasculature to infect the liver. This journey requires distinct …

In addition to transporting oxygen and carbon dioxide to and from the tissues, a range of
other functions are attributed to red blood cells (RBCs) of vertebrates. Diseases …

A family of apicomplexa-specific proteins containing AP2 DNA-binding domains (ApiAP2s)
was identified in malaria parasites. This family includes sequence-specific transcription …