Protein traffic moving from the endoplasmic reticulum (ER) to the Golgi complex in
mammalian cells passes through the tubulovesicular membrane clusters of the ER-Golgi …

Eukaryotic life depends on the spatial and temporal organization of cellular membrane
systems. Recent advances in understanding the machinery of vesicle transport have …

Amyloid is associated with debilitating human ailments including Alzheimer's and prion
diseases. Biochemical, biophysical, and imaging analyses revealed that fibers produced by …

In vitro synthesis of endoplasmic reticulum-derived transpofl vesicles has been reconstituted
with washed membranes and three soluble proteins (Sarl p, Secl3p complex, and Sec23p …

Newly synthesized proteins that leave the endoplasmic reticulum (ER) are funnelled through
the Golgi complex before being sorted for transport to their different final destinations …

Dilysine motifs in cytoplasmic domains of transmembrane proteins are signals for their
continuous retrieval from the Golgi back to the endoplasmic reticulum (El?). We describe a …

Mouse hepatitis coronavirus (MHV) buds into pleomorphic membrane structures with
features expected of the intermediate compartment between the ER and the Golgi complex …

The trafficking of proteins within eukaryotic cells is achieved by the capture of cargo and
targeting molecules into vesicles that bud from a donor membrane and deliver their contents …

▪ Abstract Green fluorescent protein chimerae acting as reporters for protein localization and
trafficking within the secretory membrane system of living cells have been used in a wide …

Transport of membranes and proteins in eukaryotic cells is mediated by vesicular carriers.
Here we review the biogenesis and functions of COPI vesicles, carriers that operate in the …