TGF‐β1/Smads and miR‐21 in Renal Fibrosis and Inflammation

A Loboda, M Sobczak, A Jozkowicz… - Mediators of …, 2016 - Wiley Online Library
Renal fibrosis, irrespective of its etiology, is a final common stage of almost all chronic
kidney diseases. Increased apoptosis, epithelial‐to‐mesenchymal transition, and …

Clinical and molecular biomarkers for diagnosis and staging of NAFLD

S Di Mauro, A Scamporrino, A Filippello… - International journal of …, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most common hepatic pathology in
industrialized countries, affecting about 25% of the general population. NAFLD is a benign …

Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-κB signaling pathway

D Ren, Q Yang, Y Dai, W Guo, H Du, L Song, X Peng - Molecular cancer, 2017 - Springer
Background The primary issue arising from prostate cancer (PCa) is its high prevalence to
metastasize to bone, which severely affects the quality of life and survival time of PCa …

Five freely circulating miRNAs and bone tissue miRNAs are associated with osteoporotic fractures

C Seeliger, K Karpinski, AT Haug… - Journal of Bone and …, 2014 - academic.oup.com
Osteoporosis as a systemic skeletal disorder is characterized by increased bone fragility and
the risk of fractures. According to the World Health Organization, osteoporosis is one of the …

MicroRNAs in renal fibrosis

ACK Chung, HY Lan - Frontiers in physiology, 2015 - frontiersin.org
MicroRNAs (miRNAs) are endogenous short non-coding RNAs that regulate most of
important cellular processes by inhibiting gene expression through the post-transcriptional …

MicroRNAs in chronic kidney disease: four candidates for clinical application

LJF Peters, J Floege, EAL Biessen… - International journal of …, 2020 - mdpi.com
There are still major challenges regarding the early diagnosis and treatment of chronic
kidney disease (CKD), which is in part due to the fact that its pathophysiology is very …

[HTML][HTML] Age-and glycemia-related miR-126-3p levels in plasma and endothelial cells

F Olivieri, M Bonafè, L Spazzafumo, M Gobbi… - Aging (Albany …, 2014 - ncbi.nlm.nih.gov
Abstract Circulating miR-126-3p levels were determined in 136 healthy subjects (CTRs)
aged 20-90 years and 193 patients with type-2 diabetes mellitus (T2DMs) aged 40-80 years …

[HTML][HTML] New approaches to diagnose and target reproductive failure in cattle

KG Pohler, ST Reese, GA Franco… - Animal …, 2020 - SciELO Brasil
Reproductive failure and pregnancy loss in cattle are some of the largest economic burdens
to cattle producers and one of most perplexing factors influencing management decisions …

Biomarkers of migraine: an integrated evaluation of preclinical and clinical findings

C Demartini, M Francavilla, AM Zanaboni… - International journal of …, 2023 - mdpi.com
In recent years, numerous efforts have been made to identify reliable biomarkers useful in
migraine diagnosis and progression or associated with the response to a specific treatment …

Disease-and headache-specific microRNA signatures and their predicted mRNA targets in peripheral blood mononuclear cells in migraineurs: role of inflammatory …

T Aczél, B Benczik, B Ágg, T Körtési, P Urbán… - The Journal of …, 2022 - Springer
Background Migraine is a primary headache with genetic susceptibility, but the
pathophysiological mechanisms are poorly understood, and it remains an unmet medical …