[HTML][HTML] The many facets of therapy resistance and tumor recurrence in glioblastoma

A Goenka, D Tiek, X Song, T Huang, B Hu, SY Cheng - Cells, 2021 - mdpi.com
Glioblastoma (GBM) is the most lethal type of primary brain cancer. Standard care using
chemo-and radio-therapy modestly increases the overall survival of patients; however …

[HTML][HTML] The emerging role of the KCTD proteins in cancer

A Angrisani, A Di Fiore, E De Smaele… - Cell Communication and …, 2021 - Springer
The human family of Potassium (K+) Channel Tetramerization Domain (KCTD) proteins
counts 25 members, and a significant number of them are still only partially characterized …

[HTML][HTML] Immunological characteristics of alternative splicing profiles related to prognosis in bladder cancer

F Ye, Y Liang, Z Cheng, Y Liu, J Hu, W Li… - Frontiers in …, 2022 - frontiersin.org
Several studies have found that pathological imbalance of alterative splicing (AS) events is
associated with cancer susceptibility. carcinogenicity. Nevertheless, the relationship …

[HTML][HTML] ETS1-activated SNHG10 exerts oncogenic functions in glioma via targeting miR-532-3p/FBXL19 axis

L Jin, S Huang, C Guan, S Chang - Cancer Cell International, 2020 - Springer
Background In past few years, long non-coding RNAs (lncRNAs) have been reported to play
regulatory roles during cancer progression. LncRNA SNHG10 has been explored in several …

[HTML][HTML] Advanced bioinformatics analysis and genetic technologies for targeting autophagy in glioblastoma multiforme

AJ Manea, SK Ray - Cells, 2023 - mdpi.com
As the most malignant primary brain tumor in adults, a diagnosis of glioblastoma multiforme
(GBM) continues to carry a poor prognosis. GBM is characterized by cytoprotective …

[HTML][HTML] KCTD15 acts as an anti-tumor factor in colorectal cancer cells downstream of the demethylase FTO and the m6A reader YTHDF2

FY Zhang, L Wu, TN Zhang, HH Chen - Communications Biology, 2024 - nature.com
Abstract Potassium Channel Tetramerization Domain Containing 15 (KCTD15) participates
in the carcinogenesis of several solid malignancies; however, its role in colorectal cancer …

[HTML][HTML] Identification and validation of a prognostic immune-related alternative splicing events signature for glioma

M Wang, Z Zhou, J Zheng, W Xiao, J Zhu… - Frontiers in …, 2021 - frontiersin.org
Background Glioma is the most common malignant brain tumor in adults, with its tumor-
promoting immune microenvironment always being intricate to handle with. Amounts of …

[HTML][HTML] Characterization of alternative splicing events and prognostic signatures in gastric cancer

N Zhu, Y Zhao, W Yan, L Wei, Q Sang, J Li, B Liu… - Cancer Cell …, 2024 - Springer
Background Accumulating evidences indicate that the specific alternative splicing (AS)
events are linked to the occurrence and prognosis of gastric cancer (GC). Nevertheless, the …

[HTML][HTML] Comprehensive characterization of 11 prognostic alternative splicing events in ovarian cancer interacted with the immune microenvironment

C Yue, T Zhao, S Zhang, Y Liu, G Zheng, Y Zhang - Scientific Reports, 2022 - nature.com
Alternative splicing (AS) events play a crucial role in the tumorigenesis and progression of
cancer. Transcriptome data and Percent Spliced In (PSI) values of ovarian cancer patients …

[HTML][HTML] Immune marker signature helps to predict survival in uveal melanoma

LS Pan, Z Ackbarkha, J Zeng, ML Huang… - Mathematical …, 2021 - aimspress.com
The detailed molecular function of tumor microenvironment (TEM) in uveal melanoma (UVM)
remains unclear. This study generated the immune index and the stromal index scores by …