Zebrafish as an emerging model for studying complex brain disorders

AV Kalueff, AM Stewart, R Gerlai - Trends in pharmacological sciences, 2014 - cell.com
The zebrafish (Danio rerio) is rapidly becoming a popular model organism in
pharmacogenetics and neuropharmacology. Both larval and adult zebrafish are currently …

The role of zebrafish and laboratory rodents in schizophrenia research

V Langova, K Vales, P Horka, J Horacek - Frontiers in Psychiatry, 2020 - frontiersin.org
Schizophrenia is a severe disorder characterized by positive, negative and cognitive
symptoms, which are still not fully understood. The development of efficient antipsychotics …

Developmental Effects of Cannabidiol and Δ9-Tetrahydrocannabinol in Zebrafish

DR Carty, C Thornton, JH Gledhill… - Toxicological …, 2018 - academic.oup.com
Cannabidiol (CBD) has gained much attention in the past several years for its therapeutic
potential in the treatment of drug-resistant epilepsy, such as Dravet syndrome. Although …

Zebrafish (Danio rerio) as an ecotoxicological model for Nanomaterial induced toxicity profiling

YK Mishra, SK Verma, A Nandi… - Precision …, 2021 - portal.findresearcher.sdu.dk
With the advancement of technologies, the evolution of nanoscience is occurring at a rapid
pace. The demand for nanomaterials in various industries has increased. However, they …

The behavioral effects of acute Δ9-tetrahydrocannabinol and heroin (diacetylmorphine) exposure in adult zebrafish

AM Stewart, AV Kalueff - Brain research, 2014 - Elsevier
The use of psychotropic drugs in clinical and translational brain research continues to grow,
and the need for novel experimental models and screens is becoming widely recognized …

[HTML][HTML] Understanding the neurobiological effects of drug abuse: Lessons from zebrafish models

TE Müller, BD Fontana, KT Bertoncello… - Progress in Neuro …, 2020 - Elsevier
Drug abuse and brain disorders related to drug comsumption are public health problems
with harmful individual and social consequences. The identification of therapeutic targets …

Multigenerational consequences of early-life cannabinoid exposure in zebrafish

DR Carty, ZS Miller, C Thornton, Z Pandelides… - Toxicology and applied …, 2019 - Elsevier
Abstract While Δ 9-tetrahydrocannabinol (THC) has been widely studied in the realm of
developmental and reproductive toxicology, few studies have investigated potential toxicities …

Analysis of the uptake, metabolism, and behavioral effects of cannabinoids on zebrafish larvae

JC Achenbach, J Hill, JPM Hui, MG Morash, F Berrue… - Zebrafish, 2018 - liebertpub.com
The Cannabis sativa plant contains numerous phytocannabinoids and terpenes with known
or potential biological activity. For decades, plant breeders have been breeding the …

Ethanol and cannabinoids interact to alter behavior in a zebrafish fetal alcohol spectrum disorder model

O Boa‐Amponsem, C Zhang… - Birth defects …, 2019 - Wiley Online Library
Background Recent work suggests that endocannabinoids (eCBs) may signal through the
sonic hedgehog signaling pathway. We therefore hypothesized that combined ethanol and …

[HTML][HTML] Different developmental insecticide exposure windows trigger distinct locomotor phenotypes in the early life stages of zebrafish

M von Wyl, S Könemann, C Vom Berg - Chemosphere, 2023 - Elsevier
Due to their extensive use and high biological activity, insecticides largely contribute to loss
of biodiversity and environmental pollution. The regulation of insecticides by authorities is …