Curcumin is the active ingredient in the traditional herbal remedy and dietary spice turmeric
(Curcuma longa). Curcumin has a surprisingly wide range of beneficial properties, including …

Curcumin, a yellow pigment from Curcuma longa, is a major component of turmeric and is
commonly used as a spice and food-coloring agent. It is also used as a cosmetic and in …

Cyclooxygenase (COX), the key enzyme required for the conversion of arachidonic acid to
prostaglandins was first identified over 20 years ago. Drugs, like aspirin, that inhibit …

Tumor-promoting inflammation is one of the hallmarks of cancer. It has been shown that
cancer development is strongly influenced by both chronic and acute inflammation process …

Nonsteroidal anti-inflammatory drugs (NSAIDs) represent one of the most highly utilized
classes of pharmaceutical agents in medicine. All NSAIDs act through inhibiting …

Background Patients with familial adenomatous polyposis have a nearly 100 percent risk of
colorectal cancer. In this disease, the chemopreventive effects of nonsteroidal …

To explore the role of cyclooxygenase (COX) in endothelial cell migration and angiogenesis,
we have used two in vitro model systems involving coculture of endothelial cells with colon …

Numerous experimental, epidemiologic, and clinical studies suggest that nonsteroidal anti-
inflammatory drugs (NSAIDs), particularly the highly selective cyclooxygenase (COX)-2 …

Evidence clearly shows a chemopreventive effect for aspirin and other non-steroidal anti-
inflammatory drugs (NSAIDs) on colorectal cancer and probably other cancer types; …

Macroscale biomaterials, such as preformed implantable scaffolds and injectable soft
materials, possess powerful synergies with anti-cancer immunotherapies. Immunotherapies …