What makes Aspergillus fumigatus a successful pathogen? Genes and molecules involved in invasive aspergillosis

A Abad, JV Fernández-Molina, J Bikandi… - Revista iberoamericana …, 2010 - Elsevier
Aspergillus fumigatus is an opportunistic pathogen that causes 90% of invasive aspergillosis
(IA) due to Aspergillus genus, with a 50–95% mortality rate. It has been postulated that …

Interactions of Aspergillus fumigatus Conidia with Airway Epithelial Cells: A Critical Review

CA Croft, L Culibrk, MM Moore, SJ Tebbutt - Frontiers in microbiology, 2016 - frontiersin.org
Aspergillus fumigatus is an environmental filamentous fungus that also acts as an
opportunistic pathogen able to cause a variety of symptoms, from an allergic response to a …

Molecular Epidemiology of Aspergillus fumigatus Isolates Harboring the TR34/L98H Azole Resistance Mechanism

SMT Camps, AJMM Rijs, CHW Klaassen… - Journal of clinical …, 2012 - Am Soc Microbiol
ABSTRACT A rapid emergence of azole resistance has been observed in Aspergillus
fumigatus in The Netherlands over the past decade. The dominant resistance mechanism …

Heterogeneity among isolates reveals that fitness in low oxygen correlates with Aspergillus fumigatus virulence

CH Kowalski, SR Beattie, KK Fuller, EA McGurk… - MBio, 2016 - Am Soc Microbiol
Previous work has shown that environmental and clinical isolates of Aspergillus fumigatus
represent a diverse population that occupies a variety of niches, has extensive genetic …

Trypacidin, a Spore-Borne Toxin from Aspergillus fumigatus, Is Cytotoxic to Lung Cells

T Gauthier, X Wang, J Sifuentes Dos Santos… - PloS one, 2012 - journals.plos.org
Inhalation of Aspergillus fumigatus conidia can cause severe aspergillosis in
immunosuppressed people. A. fumigatus produces a large number of secondary …

Diversity within Aspergillus niger Clade and Description of a New Species: Aspergillus vinaceus sp. nov.

JJ Silva, BT Iamanaka, LS Ferranti, FP Massi… - Journal of Fungi, 2020 - mdpi.com
Diversity of species within Aspergillus niger clade, currently represented by A. niger sensu
stricto and A. welwitshiae, was investigated combining three-locus gene sequences …

Investigating clinical issues by genotyping of medically important fungi: why and how?

A Alanio, M Desnos-Ollivier… - Clinical microbiology …, 2017 - Am Soc Microbiol
Genotyping studies of medically important fungi have addressed elucidation of outbreaks,
nosocomial transmissions, infection routes, and genotype-phenotype correlations, of which …

[HTML][HTML] Diversity and movement of indoor Alternaria alternata across the mainland USA

JHC Woudenberg, NA Van Der Merwe… - Fungal Genetics and …, 2015 - Elsevier
Alternaria spp. from sect. Alternaria are frequently associated with hypersensitivity
pneumonitis, asthma and allergic fungal rhinitis and sinusitis. Since Alternaria is …

Molecular epidemiology of Aspergillus fumigatus: an in-depth genotypic analysis of isolates involved in an outbreak of invasive aspergillosis

J Guinea, D García de Viedma, T Peláez… - Journal of clinical …, 2011 - Am Soc Microbiol
We recently reported an outbreak of invasive aspergillosis in the major heart surgery unit of
Hospital Gregorio Marañón, Madrid, Spain (T. Peláez, P. Muñoz, J. Guinea, M. Valerio, M …

Isolate-Dependent Growth, Virulence, and Cell Wall Composition in the Human Pathogen Aspergillus fumigatus

N Amarsaikhan, EM O'Dea, A Tsoggerel, H Owegi… - PloS one, 2014 - journals.plos.org
The ubiquitous fungal pathogen Aspergillus fumigatus is a mediator of allergic sensitization
and invasive disease in susceptible individuals. The significant genetic and phenotypic …