NAT10-mediated N4-acetylcytidine modification is required for meiosis entry and progression in male germ cells

L Chen, WJ Wang, Q Liu, YK Wu, YW Wu… - Nucleic acids …, 2022 - academic.oup.com
Post-transcriptional RNA modifications critically regulate various biological processes. N 4-
acetylcytidine (ac4C) is an epi-transcriptome, which is highly conserved in all species …

Recent advances on the structure and function of RNA acetyltransferase Kre33/NAT10

S Sleiman, F Dragon - Cells, 2019 - mdpi.com
Ribosome biogenesis is one of the most energy demanding processes in the cell. In
eukaryotes, the main steps of this process occur in the nucleolus and include pre-ribosomal …

ac4C RNA modification in Cancer: Unraveling Multifaceted Roles and Promising Therapeutic Horizons

W Ouyang, Z Huang, K Wan, T Nie, H Chen, H Yao - Cancer Letters, 2024 - Elsevier
RNA modifications play a crucial role in cancer development, profoundly influencing various
stages of the RNA lifecycle. These stages encompass nuclear processing, nuclear export …

Dissection of mRNA ac4C acetylation modifications in AC and Nr fruits: insights into the regulation of fruit ripening by ethylene

L Ma, Y Zheng, Z Zhou, Z Deng, J Tan, C Bai, A Fu… - Molecular …, 2024 - Springer
Abstract N4-acetylcytidine (ac4C) modification of mRNA has been shown to be present in
plant RNAs, but its regulatory function in plant remains largely unexplored. In this study, we …

Profound changes in cerebrospinal fluid proteome and metabolic profile are associated with congenital hydrocephalus

A Requena-Jimenez, M Nabiuni… - Journal of Cerebral …, 2021 - journals.sagepub.com
The aetiology of congenital hydrocephalus (cHC) has yet to be resolved. cHC manifests late
in rodent gestation, and by 18–22 weeks in human fetuses, coinciding with the start of the …

Molecular Profiling of Epitranscriptomes in Extracellular Matrix Detached Cancer Cells

MH Dalhat - 2022 - platform.almanhal.com
Abstract Introduction & Aim: Epitranscriptomes are modifications on RNA transcripts that
promote RNA metabolisms such as RNA stability, RNA-mediated decay, RNA splicing, and …