Progesterone and estrogen signaling in the endometrium: what goes wrong in endometriosis?
In the healthy endometrium, progesterone and estrogen signaling coordinate in a tightly
regulated, dynamic interplay to drive a normal menstrual cycle and promote an embryo …
regulated, dynamic interplay to drive a normal menstrual cycle and promote an embryo …
Uterine glands: developmental biology and functional roles in pregnancy
AM Kelleher, FJ DeMayo, TE Spencer - Endocrine reviews, 2019 - academic.oup.com
All mammalian uteri contain glands in the endometrium that develop only or primarily after
birth. Gland development or adenogenesis in the postnatal uterus is intrinsically regulated …
birth. Gland development or adenogenesis in the postnatal uterus is intrinsically regulated …
Development of organoids from mouse and human endometrium showing endometrial epithelium physiology and long-term expandability
M Boretto, B Cox, M Noben, N Hendriks… - …, 2017 - journals.biologists.com
The endometrium, which is of crucial importance for reproduction, undergoes dynamic cyclic
tissue remodeling. Knowledge of its molecular and cellular regulation is poor, primarily …
tissue remodeling. Knowledge of its molecular and cellular regulation is poor, primarily …
[HTML][HTML] In situ delivery of apoptotic bodies derived from mesenchymal stem cells via a hyaluronic acid hydrogel: a therapy for intrauterine adhesions
L Xin, C Wei, X Tong, Y Dai, D Huang, J Chen, L Ma… - Bioactive materials, 2022 - Elsevier
Stem cell-based and stem cell-derived exosome-based therapies have shown promising
potential for endometrial regeneration and the clinical treatment of intrauterine adhesions …
potential for endometrial regeneration and the clinical treatment of intrauterine adhesions …
Self-renewing endometrial epithelial organoids of the human uterus
The human endometrium is essential in providing the site for implantation and maintaining
the growth and survival of the conceptus. An unreceptive endometrium and disrupted …
the growth and survival of the conceptus. An unreceptive endometrium and disrupted …
Uterine glands coordinate on-time embryo implantation and impact endometrial decidualization for pregnancy success
Uterine glands are essential for pregnancy establishment. By employing forkhead box A2
(FOXA2)-deficient mouse models coupled with leukemia inhibitory factor (LIF) repletion, we …
(FOXA2)-deficient mouse models coupled with leukemia inhibitory factor (LIF) repletion, we …
Three-dimensional culture models of human endometrium for studying trophoblast-endometrium interaction during implantation
X Li, SP Kodithuwakku, RWS Chan… - Reproductive Biology …, 2022 - Springer
During implantation, a symphony of interaction between the trophoblast originated from the
trophectoderm of the implanting blastocyst and the endometrium leads to a successful …
trophectoderm of the implanting blastocyst and the endometrium leads to a successful …
The placenta: epigenetic insights into trophoblast developmental models of a generation-bridging organ with long-lasting impact on lifelong health
M Hemberger, W Dean - Physiological Reviews, 2023 - journals.physiology.org
The placenta is a unique organ system that functionally combines both maternal and fetal
cell types with distinct lineage origins. Normal placentation is critical for developmental …
cell types with distinct lineage origins. Normal placentation is critical for developmental …
Development and characterization of human fetal female reproductive tract organoids to understand Müllerian duct anomalies
VD Venkata, MFB Jamaluddin, J Goad… - Proceedings of the …, 2022 - National Acad Sciences
Müllerian ducts are paired tubular structures that give rise to most of the female reproductive
organs. Any abnormalities in the development and differentiation of these ducts lead to …
organs. Any abnormalities in the development and differentiation of these ducts lead to …
In vitro models of the human endometrium: evolution and application for women's health
HC Fitzgerald, DJ Schust, TE Spencer - Biology of reproduction, 2021 - academic.oup.com
The endometrium is the inner lining of the uterus that undergoes complex regeneration and
differentiation during the human menstrual cycle. The process of endometrial shedding …
differentiation during the human menstrual cycle. The process of endometrial shedding …