Microglia are emerging as critical regulators of neuronal function and behavior in nearly
every area of neuroscience. Initial reports focused on classical immune functions of …

Highlights•The Reactive Oxygen Species have an utmost importance in progression of
Depression.•Depression is associated with lowered concentration of anti-oxidants in …

Age-related macular degeneration (AMD) is a blinding eye disease which incidence
gradually increases with age. Inflammation participates in AMD pathogenesis, including …

Diabetic retinopathy (DR) is a diabetic complication which affects retinal function and results
in severe loss of vision and relevant retinal diseases. Retinal vascular dysfunction caused …

Neovascular age-related macular degeneration (nAMD) is a major cause of visual
impairment and blindness. Anti-vascular endothelial growth factor (VEGF) agents, such as …

Microglia, the resident immune cells in the retina and nervous system, make irreplaceable
contributions to the maintenance of normal homeostasis and immune surveillance of these …

Glaucoma is the second leading cause of blindness worldwide, affecting~ 80 million people
by 2020 (,). The condition is characterized by a progressive loss of retinal ganglion cells …

Retinal neurodegeneration is predominantly reported as the apoptosis or impaired function
of the photoreceptors. Retinal degeneration is a major causative factor of irreversible vision …

Diabetic retinopathy (DR) is associated with retinal neovascularization, hard exudates,
inflammation, oxidative stress and cell death, leading to vision loss. Anti-vascular …

Microglia are the main resident immune cells of the nervous system and as such they are
involved in multiple roles ranging from tissue homeostasis to response to insults and circuit …