Behavioral and neurobiological mechanisms of pavlovian and instrumental extinction learning
This article reviews the behavioral neuroscience of extinction, the phenomenon in which a
behavior that has been acquired through Pavlovian or instrumental (operant) learning …
behavior that has been acquired through Pavlovian or instrumental (operant) learning …
Functional heterogeneity within rat orbitofrontal cortex in reward learning and decision making
A Izquierdo - Journal of Neuroscience, 2017 - Soc Neuroscience
Rat orbitofrontal cortex (OFC) is located in the dorsal bank of the rhinal sulcus, and is
divided into the medial orbital area, ventral orbital area, ventrolateral orbital area, lateral …
divided into the medial orbital area, ventral orbital area, ventrolateral orbital area, lateral …
Prefrontal-hippocampal interactions supporting the extinction of emotional memories: the retrieval stopping model
MC Anderson, SB Floresco - Neuropsychopharmacology, 2022 - nature.com
Neuroimaging has revealed robust interactions between the prefrontal cortex and the
hippocampus when people stop memory retrieval. Efforts to stop retrieval can arise when …
hippocampus when people stop memory retrieval. Efforts to stop retrieval can arise when …
Top‐down and bottom‐up control of stress‐coping
ER de Kloet, SF de Kloet, CS de Kloet… - Journal of …, 2019 - Wiley Online Library
In this 30th anniversary issue review, we focus on the glucocorticoid modulation of limbic‐
prefrontocortical circuitry during stress‐coping. This action of the stress hormone is mediated …
prefrontocortical circuitry during stress‐coping. This action of the stress hormone is mediated …
Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum
SF de Kloet, B Bruinsma, H Terra, TS Heistek… - Nature …, 2021 - nature.com
The medial prefrontal cortex (mPFC) steers goal-directed actions and withholds
inappropriate behavior. Dorsal and ventral mPFC (dmPFC/vmPFC) circuits have distinct …
inappropriate behavior. Dorsal and ventral mPFC (dmPFC/vmPFC) circuits have distinct …
Consolidating the circuit model for addiction
Addiction is a disease characterized by compulsive drug seeking and consumption
observed in 20–30% of users. An addicted individual will favor drug reward over natural …
observed in 20–30% of users. An addicted individual will favor drug reward over natural …
Dynamics of social representation in the mouse prefrontal cortex
DR Levy, T Tamir, M Kaufman, A Parabucki… - Nature …, 2019 - nature.com
The prefrontal cortex (PFC) plays an important role in regulating social functions in
mammals, and its dysfunction has been linked to social deficits in neurodevelopmental …
mammals, and its dysfunction has been linked to social deficits in neurodevelopmental …
The effects of early life stress on impulsivity
EO Sanchez, DA Bangasser - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Elevated impulsivity is a symptom shared by various psychiatric disorders such as
substance use disorder, bipolar disorder, and attention-deficit/hyperactivity disorder …
substance use disorder, bipolar disorder, and attention-deficit/hyperactivity disorder …
Prefrontal cortical projection neurons targeting dorsomedial striatum control behavioral inhibition
H Terra, B Bruinsma, SF de Kloet, M van der Roest… - Current Biology, 2020 - cell.com
A neural pathway from prefrontal cortex (PFC) to dorsal striatum (DS) has been suggested to
mediate cognitive control of behavior, including proactive inhibitory control and attention …
mediate cognitive control of behavior, including proactive inhibitory control and attention …
Endophenotype trait domains for advancing gene discovery in autism spectrum disorder
Autism spectrum disorder (ASD) is associated with a diverse range of etiological processes,
including both genetic and non-genetic causes. For a plurality of individuals with ASD, it is …
including both genetic and non-genetic causes. For a plurality of individuals with ASD, it is …