The role of taurine in mitochondria health: more than just an antioxidant

CJ Jong, P Sandal, SW Schaffer - Molecules, 2021 - mdpi.com
Taurine is a naturally occurring sulfur-containing amino acid that is found abundantly in
excitatory tissues, such as the heart, brain, retina and skeletal muscles. Taurine was first …

Brain manganese and the balance between essential roles and neurotoxicity

RC Balachandran, S Mukhopadhyay, D McBride… - Journal of Biological …, 2020 - ASBMB
Manganese (Mn) is an essential micronutrient required for the normal development of many
organs, including the brain. Although its roles as a cofactor in several enzymes and in …

Copper, iron, and manganese toxicity in neuropsychiatric conditions

B Tarnacka, A Jopowicz, M Maślińska - International journal of molecular …, 2021 - mdpi.com
Copper, manganese, and iron are vital elements required for the appropriate development
and the general preservation of good health. Additionally, these essential metals play key …

New insights on the role of manganese in Alzheimer's disease and Parkinson's disease

AC Martins Jr, P Morcillo, OM Ijomone… - International journal of …, 2019 - mdpi.com
Manganese (Mn) is an essential trace element that is naturally found in the environment and
is necessary as a cofactor for many enzymes and is important in several physiological …

The crucial role of oxidative stress in non-alcoholic fatty liver disease-induced male reproductive toxicity: the ameliorative effects of Iranian indigenous probiotics

MM Ommati, H Li, A Jamshidzadeh… - Naunyn-Schmiedeberg's …, 2022 - Springer
Several studies have focused on the high potential effects of probiotics on the reproductive
system. However, there is a paucity of information regarding the ameliorative intracellular …

Reversal and preventive pleiotropic mechanisms involved in the antipsychotic-like effect of taurine, an essential β-amino acid in ketamine-induced experimental …

B Ben-Azu, CI Uruaka, AM Ajayi, TA Jarikre… - Neurochemical …, 2023 - Springer
Schizophrenia is a life disabling, multisystem neuropsychiatric disease mostly derived from
complex epigenetic-mediated neurobiological changes causing behavioural deficits …

N-acetyl cysteine treatment mitigates biomarkers of oxidative stress in different tissues of bile duct ligated rats

MM Ommati, A Amjadinia, K Mousavi, N Azarpira… - Stress, 2021 - Taylor & Francis
Cholestasis is a multifaceted clinical complication. Obstructive jaundice induced by bile duct
ligation (BDL) is known as an animal model to investigate cholestasis and its associated …

Mechanisms of manganese-induced neurotoxicity and the pursuit of neurotherapeutic strategies

E Pajarillo, I Nyarko-Danquah, A Digman… - Frontiers in …, 2022 - frontiersin.org
Chronic exposure to elevated levels of manganese via occupational or environmental
settings causes a neurological disorder known as manganism, resembling the symptoms of …

Impact of environmental risk factors on mitochondrial dysfunction, neuroinflammation, protein misfolding, and oxidative stress in the etiopathogenesis of parkinson's …

M Huang, A Bargues-Carot, Z Riaz, H Wickham… - International journal of …, 2022 - mdpi.com
As a prevalent progressive neurodegenerative disorder, Parkinson's disease (PD) is
characterized by the neuropathological hallmark of the loss of nigrostriatal dopaminergic …

[HTML][HTML] Manganese toxicity

GR Evans, LN Masullo - StatPearls [Internet], 2023 - ncbi.nlm.nih.gov
Objectives: Identify the etiology of manganese toxicity. Describe the appropriate evaluation
of patients suffering from suspected manganese toxicity. Review the management options …