Damage-mediated macrophage polarization in sterile inflammation

G Koncz, V Jenei, M Tóth, E Váradi, B Kardos… - Frontiers in …, 2023 - frontiersin.org
Most of the leading causes of death, such as cardiovascular diseases, cancer, dementia,
neurodegenerative diseases, and many more, are associated with sterile inflammation …

Macrophages in aseptic loosening: Characteristics, functions, and mechanisms

Y Cong, Y Wang, T Yuan, Z Zhang, J Ge… - Frontiers in …, 2023 - frontiersin.org
Aseptic loosening (AL) is the most common complication of total joint arthroplasty (TJA).
Both local inflammatory response and subsequent osteolysis around the prosthesis are the …

Quantitative proteomics analysis of COVID-19 patients: Fetuin-A and tetranectin as potential modulators of innate immune responses

B Alghanem, FA Mansour, H Shaibah, K Almuhalhil… - Heliyon, 2023 - cell.com
Abstract Treatment of severe cases of coronavirus disease 2019 (COVID-19) is extremely
important to minimize death and end-organ damage. Here we performed a proteomic …

Lactate and lactylation in macrophage metabolic reprogramming: current progress and outstanding issues

B Xu, Y Liu, N Li, Q Geng - Frontiers in Immunology, 2024 - frontiersin.org
It is commonly known that different macrophage phenotypes play specific roles in different
pathophysiological processes. In recent years, many studies have linked the phenotypes of …

PACMIDS: Patient-Centered, AI-Enabled, Molecular-Informed Data Fabric for Clinical Treatment Decision Support

J Kowalski, Q Xu, M Ylagan… - AI in Precision …, 2024 - liebertpub.com
Introduction: The demand for comprehensive data resources has surged due to
advancements in research aimed at tackling complex questions. Data integration techniques …

[图书][B] Disulfide HMGB1-Induced Immune Activation During and Following Ischemia-Reperfusion Injury in Human Orthotopic Liver Transplantation

AQ Terry - 2023 - search.proquest.com
Ischemia-reperfusion injury (IRI) is an intrinsic risk of solid organ transplantation due to the
cellular damage and subsequent immune activation induced by current allograft …