[HTML][HTML] Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis

Y Feng, M Spezia, S Huang, C Yuan, Z Zeng, L Zhang… - Genes & diseases, 2018 - Elsevier
As the most commonly occurring cancer in women worldwide, breast cancer poses a
formidable public health challenge on a global scale. Breast cancer consists of a group of …

Triple-negative breast cancer: A run-through of features, classification and current therapies

M Manjunath, B Choudhary - Oncology Letters, 2021 - spandidos-publications.com
Breast cancer is the most prevalent cancer in women worldwide. Triple-negative breast
cancer (TNBC) is characterized by the lack of expression of estrogen receptor, progesterone …

[HTML][HTML] How shall we treat early triple-negative breast cancer (TNBC): from the current standard to upcoming immuno-molecular strategies

JH Park, JH Ahn, SB Kim - ESMO open, 2018 - Elsevier
Triple-negative breast cancer (TNBC) is a long-lasting orphan disease in terms of little
therapeutic progress during the past several decades and still the standard of care remains …

Triple negative breast cancer: a mountain yet to be scaled despite the triumphs

Q Wu, S Siddharth, D Sharma - Cancers, 2021 - mdpi.com
Simple Summary Triple-negative breast cancer (TNBC) is a highly aggressive subtype of
breast cancer that cannot be treated with endocrine therapy and Her2-targeted therapy …

Valproic acid and breast cancer: State of the art in 2021

A Wawruszak, M Halasa, E Okon, W Kukula-Koch… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer (BC) is the most common cancer diagnosed among women
worldwide. Despite numerous studies, the pathogenesis of BC is still poorly understood, and …

Role of hedgehog signaling in breast cancer: pathogenesis and therapeutics

NA Riobo-Del Galdo, A Lara Montero, EV Wertheimer - Cells, 2019 - mdpi.com
Breast cancer (BC) is the leading cause of cancer-related mortality in women, only followed
by lung cancer. Given the importance of BC in public health, it is essential to identify …

The “Yin and Yang” of natural compounds in anticancer therapy of triple-negative breast cancers

E Varghese, SM Samuel, M Abotaleb, S Cheema… - Cancers, 2018 - mdpi.com
Among the different types of breast cancers, triple-negative breast cancers (TNBCs) are
highly aggressive, do not respond to conventional hormonal/human epidermal growth factor …

miR-29b-3p promotes progression of MDA-MB-231 triple-negative breast cancer cells through downregulating TRAF3

B Zhang, D Shetti, C Fan, K Wei - Biological research, 2019 - Springer
Background Breast cancer is the second common malignant cancer among females
worldwide. Accumulating studies have indicated that deregulation of miRNA expression in …

Therapeutic landscape in mutational triple negative breast cancer

Y Shi, J Jin, W Ji, X Guan - Molecular cancer, 2018 - Springer
Triple negative breast cancer (TNBC) is a heterogeneous disease with aggressive behavior
and poor prognosis. Genomic sequencing has detected a distinctive mutational portrait of …

Dietary phenolics against breast cancer. A critical evidence-based review and future perspectives

MÁ Ávila-Gálvez, JA Giménez-Bastida… - International journal of …, 2020 - mdpi.com
Breast cancer (BC) is the most common malignancy and the leading cause of cancer-related
death in adult women worldwide. Over 85% of BC cases are non-hereditary, caused by …