Liver fibrosis in non-alcoholic fatty liver disease: from liver biopsy to non-invasive biomarkers in diagnosis and treatment
LJM Heyens, D Busschots, GH Koek, G Robaeys… - Frontiers in …, 2021 - frontiersin.org
An increasing percentage of people have or are at risk to develop non-alcoholic fatty liver
disease (NAFLD) worldwide. NAFLD comprises different stadia going from isolated steatosis …
disease (NAFLD) worldwide. NAFLD comprises different stadia going from isolated steatosis …
[HTML][HTML] Metabolic drivers of non-alcoholic fatty liver disease
KK Bence, MJ Birnbaum - Molecular metabolism, 2021 - Elsevier
Background The incidence of non-alcoholic fatty liver disease (NAFLD) is rapidly increasing
worldwide parallel to the global obesity epidemic. NAFLD encompasses a range of liver …
worldwide parallel to the global obesity epidemic. NAFLD encompasses a range of liver …
Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD
G Lee, HJ You, JS Bajaj, SK Joo, J Yu, S Park… - Nature …, 2020 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is associated with obesity but also found in non-
obese individuals. Gut microbiome profiles of 171 Asians with biopsy-proven NAFLD and 31 …
obese individuals. Gut microbiome profiles of 171 Asians with biopsy-proven NAFLD and 31 …
[HTML][HTML] rs641738C> T near MBOAT7 is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis
K Teo, KWM Abeysekera, L Adams, E Aigner… - Journal of …, 2021 - Elsevier
Background & Aims A common genetic variant near MBOAT7 (rs641738C> T) has been
previously associated with hepatic fat and advanced histology in NAFLD; however, these …
previously associated with hepatic fat and advanced histology in NAFLD; however, these …
[HTML][HTML] A polygenic risk score to refine risk stratification and prediction for severe liver disease by clinical fibrosis scores
Background & Aims A polygenic risk score based on well-known genetic variants in
PNPLA3, TM6SF2, MBOAT7, and GCKR predicts hepatic fat content (polygenic risk score …
PNPLA3, TM6SF2, MBOAT7, and GCKR predicts hepatic fat content (polygenic risk score …
[HTML][HTML] Diagnosis and management of secondary causes of steatohepatitis
R Liebe, I Esposito, HH Bock, S Vom Dahl, J Stindt… - Journal of …, 2021 - Elsevier
The term non-alcoholic liver disease (NAFLD) was originally coined to describe hepatic fat
deposition as part of the metabolic syndrome. However, a variety of rare hereditary liver and …
deposition as part of the metabolic syndrome. However, a variety of rare hereditary liver and …
[HTML][HTML] Clinical assessment and management of liver fibrosis in non-alcoholic fatty liver disease
A Campos-Murguía, A Ruiz-Margáin… - World journal of …, 2020 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is among the most frequent etiologies of cirrhosis
worldwide, and it is associated with features of metabolic syndrome; the key factor …
worldwide, and it is associated with features of metabolic syndrome; the key factor …
Toward genetic prediction of nonalcoholic fatty liver disease trajectories: PNPLA3 and beyond
M Krawczyk, R Liebe, F Lammert - Gastroenterology, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is on the verge of becoming the leading cause of
liver disease. NAFLD develops at the interface between environmental factors and inherited …
liver disease. NAFLD develops at the interface between environmental factors and inherited …
Interaction effect between NAFLD severity and high carbohydrate diet on gut microbiome alteration and hepatic de novo lipogenesis
Nonalcoholic fatty liver disease (NAFLD) is associated with high carbohydrate (HC) intake.
We investigated whether the relationship between carbohydrate intake and NAFLD is …
We investigated whether the relationship between carbohydrate intake and NAFLD is …
Genetics is of the essence to face NAFLD
Nonalcoholic fatty liver disease (NAFLD) is the commonest cause of chronic liver disease
worldwide. It is closely related to obesity, insulin resistance (IR) and dyslipidemia so much …
worldwide. It is closely related to obesity, insulin resistance (IR) and dyslipidemia so much …