Nanoparticles for drug delivery to the anterior segment of the eye

DR Janagam, L Wu, TL Lowe - Advanced drug delivery reviews, 2017 - Elsevier
Commercially available ocular drug delivery systems are effective but less efficacious to
manage diseases/disorders of the anterior segment of the eye. Recent advances in …

Chitosan-based nanoparticles as drug delivery systems: a review on two decades of research

S Naskar, K Kuotsu, S Sharma - Journal of drug targeting, 2019 - Taylor & Francis
Chitosan (CS) is one of the most functional natural biopolymer widely used in the
pharmaceutical field due to its biocompatibility and biodegradability. These privileges lead …

Nanomaterial-based ophthalmic drug delivery

G Xie, S Lin, F Wu, J Liu - Advanced drug delivery reviews, 2023 - Elsevier
The low bioavailability and side effects of conventional drugs for eye disease necessitate the
development of efficient drug delivery systems. Accompanying the developments of …

Sustained drug release by contact lenses for glaucoma treatment—A review

IM Carvalho, CS Marques, RS Oliveira… - Journal of controlled …, 2015 - Elsevier
In the context of ocular pharmacology, there is a growing need for innovative delivery
platforms for a convenient and sustained drug release into the eye, especially for chronic …

Controlled release matrices and micro/nanoparticles of chitosan with antimicrobial potential: development of new strategies for microbial control in agriculture

O Cota‐Arriola, M Onofre Cortez‐Rocha… - Journal of the …, 2013 - Wiley Online Library
The control of micro‐organisms responsible for pre‐and postharvest diseases of agricultural
products, mainly viruses and fungi, is a problem that remains unresolved, together with the …

Statistical optimization of co-loaded rifampicin and pentamidine polymeric nanoparticles for the treatment of cutaneous leishmaniasis

MM Khan, SS Zaidi, FJ Siyal, SU Khan, G Ishrat… - Journal of Drug Delivery …, 2023 - Elsevier
Topical drug delivery against cutaneous leishmaniasis (CL) serves as an effective alternate
approach to improve efficacy and reduce systemic adverse effects. The purpose of this study …

Synthesis, characterization and cytotoxic evaluation of chitosan nanoparticles: in vitro liver cancer model

SA Loutfy, HMA El-Din, MH Elberry… - Advances in Natural …, 2016 - iopscience.iop.org
To evaluate the cytotoxic effect of chitosan nanoparticles (CS-NPs) on an in vitro human liver
cancer cell model (HepG2) and their possible application as a drug delivery system, we …

Development of thermosensitive in situ gel nanoemulsions for ocular delivery of acyclovir

MM Mahboobian, M Mohammadi, Z Mansouri - Journal of Drug Delivery …, 2020 - Elsevier
The aim of the current study was to formulate thermosensitive in situ gel nanoemulsions
(NEs) containing acyclovir (ACV) for ocular drug delivery and evaluate their ex vivo corneal …

Nanoparticle systems as tools to improve drug delivery and therapeutic efficacy

D Mishra, JR Hubenak… - … A: An Official Journal of The …, 2013 - Wiley Online Library
Nanoparticle‐based drug delivery systems are appealing because, among other properties,
they are easily manufactured and have the capacity to encapsulate a wide variety of drugs …

Why chitosan could be apt candidate for glaucoma drug delivery-An overview

BN Kumara, R Shambhu, KS Prasad - International Journal of Biological …, 2021 - Elsevier
Most of the people in the world are affected by glaucoma, which leads to irreversible
blindness. Several patient friendly treatments are available, nevertheless medications lack …