Protein acetylation and deacetylation: An important regulatory modification in gene transcription

C Xia, Y Tao, M Li, T Che, J Qu - Experimental and …, 2020 - spandidos-publications.com
Cells primarily rely on proteins to perform the majority of their physiological functions, and
the function of proteins is regulated by post‑translational modifications (PTMs). The …

Histone acetylation dynamics in repair of DNA double-strand breaks

S Aricthota, PP Rana, D Haldar - Frontiers in Genetics, 2022 - frontiersin.org
Packaging of eukaryotic genome into chromatin is a major obstacle to cells encountering
DNA damage caused by external or internal agents. For maintaining genomic integrity, the …

[HTML][HTML] Histone post-translational modification and the DNA damage response

H Song, R Shen, X Liu, X Yang, K Xie, Z Guo, D Wang - Genes & Diseases, 2023 - Elsevier
DNA is highly vulnerable to spontaneous and environmental timely damage in living cells.
DNA damage may cause genetic instability and increase cancer risk if the damages are not …

[HTML][HTML] Acetylation of Histone H3 in Cancer Progression and Prognosis

P Miziak, M Baran, L Borkiewicz, T Trombik… - International Journal of …, 2024 - mdpi.com
Cancer is a multifactorial disease resulting from both genetic factors and epigenetic
changes. Histone acetylation, a post-translational modification, which alters chromatin …