A nexus of miR-1271, PAX4 and ALK/RYK influences the cytoskeletal architectures in Alzheimer's Disease and Type 2 Diabetes

P Majumder, K Chanda, D Das, BK Singh… - Biochemical …, 2021 - portlandpress.com
Alzheimer's Disease (AD) and Type 2 Diabetes (T2D) share a common hallmark of insulin
resistance. Reportedly, two non-canonical Receptor Tyrosine Kinases (RTKs), ALK and …

Protein tyrosine kinase 7 regulates EGFR/Akt signaling pathway and correlates with malignant progression in triple-negative breast cancer

NP Cui, S Qiao, S Jiang, JL Hu, TT Wang… - Frontiers in …, 2021 - frontiersin.org
Purpose Triple-negative breast cancer (TNBC), the most aggressive subtype of breast
cancer, is associated with high invasiveness, high metastatic occurrence and poor …

Long non-coding RNA MALAT1 protects against Aβ1–42 induced toxicity by regulating the expression of receptor tyrosine kinase EPHA2 via quenching miR-200a …

K Chanda, NR Jana, D Mukhopadhyay - Life Sciences, 2022 - Elsevier
Abstract Altered expressions of Receptor Tyrosine Kinases (RTK) and non-coding (nc)
RNAs are known to regulate the pathophysiology of Alzheimer's disease (AD). However …

The receptor tyrosine kinase IGF1R and its associated GPCRs are co-regulated by the noncoding RNA NEAT1 in Alzheimer's disease

P Sengupta, S Sen, D Mukhopadhyay - Gene, 2024 - Elsevier
The study is based on the complexity of Insulin like growth factor receptor (IGF1R) signaling
and its regulation by noncoding RNAs (ncRNAs). IGF1R signaling is an important cascade …

[HTML][HTML] Genome-Wide Linkage and Association of Novel Genes and Pathways with Type 2 Diabetes in Italian Families

M Amin, C Gragnoli - Aspects of Molecular Medicine, 2024 - Elsevier
Background Type 2 diabetes mellitus (T2D) stands as one of the most prevalent chronic
diseases globally, posing substantial health and economic burdens on society. Within the …

miR-145, miR-92a and miR-375 show differential expression in serum from patients with diabetic retinopathies

A Solis-Vivanco, M Santamaría-Olmedo… - Diagnostics, 2022 - mdpi.com
Diabetic retinopathies are important disabling conditions. Micro-RNAs (miRNAs) are
regulators of gene expression and diseases can change their expression. Our aim was to …

Amyloid precursor protein intra-cellular domain (AICD), Aβ and their confounding synergistic effects differentially regulate the degradome of cellular models of …

K Chanda, S Laha, R Chatterjee, D Mukhopadhyay - Gene Reports, 2021 - Elsevier
Altered expressions of protein-coding genes and microRNAs have been implicated in the
pathogenesis of Alzheimer's disease (AD). The disrupted miRNA landscape (degradome) …

Possibilities of combinatorial therapy: insulin dysregulation and the growth hormone perspective on neurodegeneration

P Sengupta, D Mukhopadhyay - Pharmacogenetics, 2021 - books.google.com
RTKs have been reported to be implicated in several neurodegenerative disorders and the
roles of insulin receptor family have emerged as a key common pathway across diseases …

[PDF][PDF] “Análisis de expresión diferencial de miRNAS en vítreo y suero de pacientes diabéticos mexicanos con micro-angiopatías de retina en comparación con …

MAS VIVANCO - 2023 - ru.dgb.unam.mx
La microangiopatía en retina representa la complicación ocular con mayor potencial
discapacitante en el paciente diabético en México. Los micro-RNAs (miRNAs) han surgido …

[PDF][PDF] Aspects of Molecular Medicine

M Amin, S Syed, R Wu, TT Postolache, C Gragnoli - researchgate.net
Background: Type 2 diabetes mellitus (T2D) stands as one of the most prevalent chronic
diseases globally, posing substantial health and economic burdens on society. Within the …