Functioning as the outermost self-renewing protective layer of the human organism, skin
protects against a multitude of harmful biological and physical stimuli. Consisting of …

Inositol displays multi-targeted effects on many biochemical pathways involved in epithelial-
mesenchymal transition (EMT). As Akt activation is inhibited by inositol, we investigated if …

Travel to space has overcome unprecedent technological challenges and this has resulted
in transfer of these technological results on Earth to better our lives. Health technology …

Highlights What are the main findings? For the first time, the in vitro effects of simulated
microgravity using a Random Positioning Machine on the ultrastructural features of human …

One of the hallmarks of microgravity-induced effects in several cellular models is
represented by the alteration of oxidative balance with the consequent accumulation of …

Background It was confirmed that simulated microgravity (SMG) led to ultrastructural
alterations and apoptosis in many types of microvascular endothelial cells. However …

Astronauts exposed to a gravity-free environment experience cardiovascular deconditioning
that causes post-spaceflight orthostatic intolerance and other pathological conditions …

The effects of microgravity on functions of the human body are well described, including
alterations in the male and female reproductive systems. In the present study, TCam-2 cells …

During space travel, astronauts will experience a unique environment that includes
continuous exposure to microgravity and stressful living conditions. Physiological adaptation …

(1) Background: The main purpose of the study was to determine whether altered gravity
might alter cell viability, improve drug delivery and modulate the expression of drug …