Biological functions of mesenchymal stem cells and clinical implications
Mesenchymal stem cells (MSCs) are isolated from multiple biological tissues—adult bone
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …
Mesenchymal stem cell-derived extracellular vesicles: toward cell-free therapeutic applications
Mesenchymal stem (stromal) cells (MSCs) are multipotent cells with the ability to differentiate
into several cell types, thus serving as a cell reservoir for regenerative medicine. Much of the …
into several cell types, thus serving as a cell reservoir for regenerative medicine. Much of the …
Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD
DA Ferenbach, JV Bonventre - Nature Reviews Nephrology, 2015 - nature.com
Acute kidney injury is an increasingly common complication of hospital admission and is
associated with high levels of morbidity and mortality. A hypotensive, septic, or toxic insult …
associated with high levels of morbidity and mortality. A hypotensive, septic, or toxic insult …
Cellular pathophysiology of ischemic acute kidney injury
JV Bonventre, L Yang - The Journal of clinical investigation, 2011 - Am Soc Clin Investig
Ischemic kidney injury often occurs in the context of multiple organ failure and sepsis. Here,
we review the major components of this dynamic process, which involves hemodynamic …
we review the major components of this dynamic process, which involves hemodynamic …
Mesenchymal stem cell: an efficient mass producer of exosomes for drug delivery
Advances in biomedical research have generated an unprecedented number of potential
targets for therapeutic intervention to treat disease or delay disease progression …
targets for therapeutic intervention to treat disease or delay disease progression …
Biodistribution, migration and homing of systemically applied mesenchymal stem/stromal cells
J Leibacher, R Henschler - Stem cell research & therapy, 2016 - Springer
Mesenchymal stem/stromal cells (MSCs) are increasingly used as an intravenously applied
cellular therapeutic. They were found to be potent in situations such as tissue repair or …
cellular therapeutic. They were found to be potent in situations such as tissue repair or …
Shear-thinning hydrogels for biomedical applications
M Guvendiren, HD Lu, JA Burdick - Soft matter, 2012 - pubs.rsc.org
Injectable hydrogels are becoming increasingly important in the fields of tissue engineering
and drug delivery due to their tunable properties, controllable degradation, high water …
and drug delivery due to their tunable properties, controllable degradation, high water …
Trophic effects of mesenchymal stem cells in tissue regeneration
Mesenchymal stem cells (MSCs) are considered to hold great therapeutic value for cell-
based therapy and for tissue regeneration in particular. Recent evidence indicates that the …
based therapy and for tissue regeneration in particular. Recent evidence indicates that the …
[HTML][HTML] Exosomes/microvesicles as a mechanism of cell-to-cell communication
Microvesicles (MVs) are circular fragments of membrane released from the endosomal
compartment as exosomes or shed from the surface membranes of most cell types. An …
compartment as exosomes or shed from the surface membranes of most cell types. An …
Pathophysiology of ischemic acute kidney injury
AA Sharfuddin, BA Molitoris - Nature Reviews Nephrology, 2011 - nature.com
Acute kidney injury (AKI) as a consequence of ischemia is a common clinical event leading
to unacceptably high morbidity and mortality, development of chronic kidney disease (CKD) …
to unacceptably high morbidity and mortality, development of chronic kidney disease (CKD) …