Ceria‐based therapeutic antioxidants for biomedical applications
The growing interest in nanomedicine over the last 20 years has carved out a research field
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …
Recent advances in models, mechanisms, biomarkers, and interventions in cisplatin-induced acute kidney injury
SJ Holditch, CN Brown, AM Lombardi… - International journal of …, 2019 - mdpi.com
Cisplatin is a widely used chemotherapeutic agent used to treat solid tumours, such as
ovarian, head and neck, and testicular germ cell. A known complication of cisplatin …
ovarian, head and neck, and testicular germ cell. A known complication of cisplatin …
Single-nuclear transcriptomics reveals diversity of proximal tubule cell states in a dynamic response to acute kidney injury
LMS Gerhardt, J Liu, K Koppitch… - Proceedings of the …, 2021 - National Acad Sciences
Acute kidney injury (AKI), commonly caused by ischemia, sepsis, or nephrotoxic insult, is
associated with increased mortality and a heightened risk of chronic kidney disease (CKD) …
associated with increased mortality and a heightened risk of chronic kidney disease (CKD) …
Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD
DA Ferenbach, JV Bonventre - Nature Reviews Nephrology, 2015 - nature.com
Acute kidney injury is an increasingly common complication of hospital admission and is
associated with high levels of morbidity and mortality. A hypotensive, septic, or toxic insult …
associated with high levels of morbidity and mortality. A hypotensive, septic, or toxic insult …
[HTML][HTML] Mechanisms and therapeutic targets of ischemic acute kidney injury
SJ Han, HT Lee - Kidney research and clinical practice, 2019 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) due to renal ischemia reperfusion (IR) is a major clinical problem
without effective therapy and is a significant and frequent cause of morbidity and mortality …
without effective therapy and is a significant and frequent cause of morbidity and mortality …
[HTML][HTML] Renal ischemia/reperfusion injury; from pathophysiology to treatment
M Malek, M Nematbakhsh - Journal of renal injury prevention, 2015 - ncbi.nlm.nih.gov
Ischemia/reperfusion injury (IRI) is caused by a sudden temporary impairment of the blood
flow to the particular organ. IRI usually is associated with a robust inflammatory and …
flow to the particular organ. IRI usually is associated with a robust inflammatory and …
[HTML][HTML] Pathophysiology of acute kidney injury
DP Basile, MD Anderson, TA Sutton - Comprehensive Physiology, 2012 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) is the leading cause of nephrology consultation and is associated
with high mortality rates. The primary causes of AKI include ischemia, hypoxia or …
with high mortality rates. The primary causes of AKI include ischemia, hypoxia or …
Cellular pathophysiology of ischemic acute kidney injury
JV Bonventre, L Yang - The Journal of clinical investigation, 2011 - Am Soc Clin Investig
Ischemic kidney injury often occurs in the context of multiple organ failure and sepsis. Here,
we review the major components of this dynamic process, which involves hemodynamic …
we review the major components of this dynamic process, which involves hemodynamic …
Immune cells in experimental acute kidney injury
HR Jang, H Rabb - Nature Reviews Nephrology, 2015 - nature.com
Acute kidney injury (AKI) prolongs hospital stay and increases mortality in various clinical
settings. Ischaemia–reperfusion injury (IRI), nephrotoxic agents and infection leading to …
settings. Ischaemia–reperfusion injury (IRI), nephrotoxic agents and infection leading to …
Neutrophil diversity and plasticity: Implications for organ transplantation
Neutrophils, as the first defenders against external microbes and stimuli, are highly active
and finely regulated innate immune cells. Emerging evidence has challenged the …
and finely regulated innate immune cells. Emerging evidence has challenged the …