Photodynamic and photothermal therapies: synergy opportunities for nanomedicine

M Overchuk, RA Weersink, BC Wilson, G Zheng - ACS nano, 2023 - ACS Publications
Tumoricidal photodynamic (PDT) and photothermal (PTT) therapies harness light to
eliminate cancer cells with spatiotemporal precision by either generating reactive oxygen …

[HTML][HTML] Brain-derived neurotrophic factor in Alzheimer's disease and its pharmaceutical potential

L Gao, Y Zhang, K Sterling, W Song - Translational Neurodegeneration, 2022 - Springer
Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

[HTML][HTML] Molecular interactions in organic nanoparticles for phototheranostic applications

KK Ng, G Zheng - Chemical reviews, 2015 - ACS Publications
Optical and photonic technologies play an important role in human progress. The bending of
light to our will has not only enabled our biological self-discovery, but has also allowed us to …

[HTML][HTML] The role of focal therapy in the management of localised prostate cancer: a systematic review

M Valerio, HU Ahmed, M Emberton, N Lawrentschuk… - European urology, 2014 - Elsevier
Context The incidence of localised prostate cancer is increasing worldwide. In light of recent
evidence, current, radical, whole-gland treatments for organ-confined disease have being …

An MRI‐sensitive, non‐photobleachable porphysome photothermal agent

TD MacDonald, TW Liu, G Zheng - Angewandte Chemie, 2014 - Wiley Online Library
Photothermal therapy makes use of photothermal sensitizers and laser light to thermally
ablate diseased tissues. Porphysome nanoparticles offer a nontoxic alternative to inorganic …

Comparison of interreader reproducibility of the prostate imaging reporting and data system and likert scales for evaluation of multiparametric prostate MRI

AB Rosenkrantz, RP Lim, M Haghighi… - American journal of …, 2013 - Am Roentgen Ray Soc
OBJECTIVE. The objective of our study was to compare interreader reproducibility of the
recently proposed “Prostate Imaging Reporting and Data System,” or “PI-RADS,” scale …

Phase II evaluation of magnetic resonance imaging guided focal laser ablation of prostate cancer

SE Eggener, A Yousuf, S Watson, S Wang… - Journal of Urology, 2016 - journals.lww.com
Purpose: Magnetic resonance imaging guided focal laser ablation is an investigational
strategy for the treatment of prostate cancer. Materials and Methods: This phase II evaluation …

An update on focal therapy for prostate cancer

M Perera, N Krishnananthan, U Lindner… - Nature Reviews …, 2016 - nature.com
Globally, the increased uptake of serum PSA level screening led to an increase in the
number of diagnoses of low-risk and intermediate-risk prostate cancer. Traditionally, these …

Proton resonance frequency shift thermometry: a review of modern clinical practices

J Blackwell, MJ Kraśny, A O'Brien… - Journal of Magnetic …, 2022 - Wiley Online Library
Magnetic resonance imaging (MRI) has become a popular modality in guiding minimally
invasive thermal therapies, due to its advanced, nonionizing, imaging capabilities and its …

Prostate cancer foci detected on multiparametric magnetic resonance imaging are histologically distinct from those not detected

AB Rosenkrantz, S Mendrinos, JS Babb… - The Journal of …, 2012 - auajournals.org
Purpose: We identified histological differences between prostate cancer foci that are
detected and missed using multiparametric magnetic resonance imaging. Materials and …