[HTML][HTML] Nrf2 regulates oxidative stress and its role in cerebral ischemic stroke
Cerebral ischemic stroke is characterized by acute ischemia in a certain part of the brain,
which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc. At present, there …
which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc. At present, there …
Neuroinflammation in acute ischemic and hemorrhagic stroke
DL Alsbrook, M Di Napoli, K Bhatia, J Biller… - Current neurology and …, 2023 - Springer
Abstract Purpose of Review This review aims to provide an overview of neuroinflammation
in ischemic and hemorrhagic stroke, including recent findings on the mechanisms and …
in ischemic and hemorrhagic stroke, including recent findings on the mechanisms and …
[HTML][HTML] The translational potential of microglia and monocyte-derived macrophages in ischemic stroke
The immune response to ischemic stroke is an area of study that is at the forefront of stroke
research and presents promising new avenues for treatment development. Upon cerebral …
research and presents promising new avenues for treatment development. Upon cerebral …
Acetyl-11-keto-beta boswellic acid (AKBA) modulates CSTC-pathway by activating SIRT-1/Nrf2-HO-1 signalling in experimental rat model of obsessive-compulsive …
Obsessive-Compulsive disorder (OCD) is a long-term and persistent mental illness
characterised by obsessive thoughts and compulsive behaviours. Numerous factors can …
characterised by obsessive thoughts and compulsive behaviours. Numerous factors can …
Targeting Nrf2 signaling pathway by quercetin in the prevention and treatment of neurological disorders: An overview and update on new developments
MY Zamanian, A Soltani, Z Khodarahmi… - Fundamental & …, 2023 - Wiley Online Library
Abstract Background: Neurological disorders (NLDs) are widely acknowledged as a
significant public health concern worldwide. Stroke, Alzheimer's disease (AD), and traumatic …
significant public health concern worldwide. Stroke, Alzheimer's disease (AD), and traumatic …
[HTML][HTML] Activation of Nrf2 to optimise immune responses to intracerebral haemorrhage
Haemorrhage into the brain parenchyma can be devastating. This manifests as
spontaneous intracerebral haemorrhage (ICH) after head trauma, and in the context of …
spontaneous intracerebral haemorrhage (ICH) after head trauma, and in the context of …
[HTML][HTML] Impact of NQO1 dysregulation in CNS disorders
L Yuhan, M Khaleghi Ghadiri, A Gorji - Journal of Translational Medicine, 2024 - Springer
Abstract NAD (P) H Quinone Dehydrogenase 1 (NQO1) plays a pivotal role in the regulation
of neuronal function and synaptic plasticity, cellular adaptation to oxidative stress …
of neuronal function and synaptic plasticity, cellular adaptation to oxidative stress …
[HTML][HTML] The role of concomitant Nrf2 targeting and stem cell therapy in cerebrovascular disease
Despite the reality that a death from cerebrovascular accident occurs every 3.5 min in the
United States, there are few therapeutic options which are typically limited to a narrow …
United States, there are few therapeutic options which are typically limited to a narrow …
[HTML][HTML] Intracerebral haemorrhage in multiple sclerosis: assessing the impact of disease-modifying medications
Multiple Sclerosis (MS) is a complex autoimmune disorder that significantly impacts the
central nervous system, leading to a range of complications. While intracranial haemorrhage …
central nervous system, leading to a range of complications. While intracranial haemorrhage …