Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

To enable survival in adverse conditions, cancer cells undergo global metabolic
adaptations. The amino acid cysteine actively contributes to cancer metabolic remodelling …

Over the last decade, hydrogen sulfide (H2S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

Hydrogen sulfide (H 2 S) is an important signaling molecule in colorectal cancer (CRC). It is
produced in the colon by the catalytic synthesis of the colonocytes' enzymatic systems and …

Cystathionine-β-synthase (CBS), the first (and rate-limiting) enzyme in the transsulfuration
pathway, is an important mammalian enzyme in health and disease. Its biochemical …

The mammalian brain is highly vulnerable to oxygen deprivation, yet the mechanism
underlying the brain's sensitivity to hypoxia is incompletely understood. Hypoxia induces …

Living longer without simultaneously extending years spent in good health (“health span”) is
an increasing societal burden, demanding new therapeutic strategies. Hydrogen sulfide …

Hydrogen sulfide (H2S) has emerged as a relevant signaling molecule in physiology, taking
its seat as a bona fide gasotransmitter akin to nitric oxide (NO) and carbon monoxide (CO) …

Abstract NF-E2-related factor 2 (NRF2) plays a crucial role in the maintenance of cellular
homeostasis by regulating various enzymes and proteins that are involved in the redox …

Reactive sulfur species, or persulfides and polysulfides, such as cysteine hydropersulfide
and glutathione persulfide, are endogenously produced in abundance in both prokaryotes …