Skeletal muscle endogenous estrogen production ameliorates the metabolic consequences of a high-fat diet in male mice

CA Unger, AK Aladhami, MC Hope III… - …, 2023 - academic.oup.com
Aims The role of skeletal muscle estrogen and its ability to mitigate the negative impact of a
high-fat diet (HFD) on obesity-associated metabolic impairments is unknown. To address …

Mediation analysis of the testosterone treatment effect to prevent type 2 diabetes in the Testosterone for Prevention of Type 2 Diabetes Mellitus trial

KP Robledo, IC Marschner… - European journal of …, 2023 - academic.oup.com
Objective To determine if testosterone treatment effect on glycaemia is mediated through
changes in total fat mass, abdominal fat mass, skeletal muscle mass, non-dominant hand …

Beyond reproduction: unraveling the impact of sex hormones on cardiometabolic health

V Xega, JL Liu - Medical Review, 2024 - degruyter.com
This review thoroughly explores the multifaceted roles of sexual hormones, emphasizing
their impact beyond reproductive functions and underscoring their significant influence on …

A Novel Tissue-Specific Insight into Sex Steroid Fluctuations Throughout the Murine Estrous Cycle

CA Unger, MC Hope III, AK Aladhami… - …, 2024 - academic.oup.com
Serum sex steroid levels fluctuate throughout the reproductive cycle. However, the degree to
which sex steroid tissue content mimics circulating content is unknown. Understanding the …