Exosomal long non-coding RNAs in lung diseases
Within the non-coding genome landscape, long non-coding RNAs (lncRNAs) and their
secretion within exosomes are a window that could further explain the regulation, the …
secretion within exosomes are a window that could further explain the regulation, the …
impact of cigarette smoking on intestinal inflammation—direct and indirect mechanisms
S Papoutsopoulou, J Satsangi… - Alimentary …, 2020 - Wiley Online Library
Background The inflammatory bowel diseases, Crohn's disease and ulcerative colitis are
related multifactorial diseases. Their pathogenesis is influenced by each individual's …
related multifactorial diseases. Their pathogenesis is influenced by each individual's …
[HTML][HTML] Ablation of long noncoding RNA MALAT1 activates antioxidant pathway and alleviates sepsis in mice
The metastasis-associated lung adenocarcinoma transcript1 (MALAT1) is a long noncoding
RNA (lncRNA) and is known for its role in cancer development and prognosis. In this study …
RNA (lncRNA) and is known for its role in cancer development and prognosis. In this study …
Omics and the search for blood biomarkers in chronic obstructive pulmonary disease. Insights from COPDGene
There is an unmet need for blood biomarkers in diagnosis and prognosis of chronic
obstructive pulmonary disease (COPD). The search for these biomarkers has been …
obstructive pulmonary disease (COPD). The search for these biomarkers has been …
Long noncoding transcriptome in chronic obstructive pulmonary disease
D Devadoss, C Long, RJ Langley… - American journal of …, 2019 - atsjournals.org
Chronic airway inflammation from recurring exposures to noxious environmental stimuli
results in a progressive and irreversible airflow limitation and the lung parenchymal damage …
results in a progressive and irreversible airflow limitation and the lung parenchymal damage …
RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD
Background Multiple gene expression studies have been performed separately in peripheral
blood, lung, and airway tissues to study COPD. We performed RNA-sequencing gene …
blood, lung, and airway tissues to study COPD. We performed RNA-sequencing gene …
Impact of the exposome on the epigenome in inflammatory bowel disease patients and animal models
S Vieujean, B Caron, V Haghnejad… - International Journal of …, 2022 - mdpi.com
Inflammatory bowel diseases (IBD) are chronic inflammatory disorders of the gastrointestinal
tract that encompass two main phenotypes, namely Crohn's disease and ulcerative colitis …
tract that encompass two main phenotypes, namely Crohn's disease and ulcerative colitis …
Cigarette smoke-induced alterations in blood: A review of research on DNA methylation and gene expression.
Worldwide, smoking remains a threat to public health, causing preventable diseases and
premature mortality. Cigarette smoke is a powerful inducer of DNA methylation and gene …
premature mortality. Cigarette smoke is a powerful inducer of DNA methylation and gene …
DNA methylation abnormalities and altered whole transcriptome profiles after switching from combustible tobacco smoking to heated tobacco products
Background: The use of heated tobacco products (HTP) has increased exponentially in
Japan since 2016; however, their effects on health remain a major concern. Methods …
Japan since 2016; however, their effects on health remain a major concern. Methods …
Development of a blood-based transcriptional risk score for chronic obstructive pulmonary disease
Rationale: The ability of peripheral blood biomarkers to assess chronic obstructive
pulmonary disease (COPD) risk and progression is unknown. Genetics and gene …
pulmonary disease (COPD) risk and progression is unknown. Genetics and gene …