Applications and limitations of dendrimers in biomedicine
Biomedicine represents one of the main study areas for dendrimers, which have proven to
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …
PAMAM dendrimer nanomolecules utilized as drug delivery systems for potential treatment of glioblastoma: a systematic review
Glioblastoma (GB) is a grade IV astrocytoma that maintains a poor prognosis with respect to
current treatment options. Despite major advancements in the fields of surgery and …
current treatment options. Despite major advancements in the fields of surgery and …
Smart nanocarriers for cancer treatment: Clinical impact and safety
Z Liao, SW Wong, HL Yeo, Y Zhao - NanoImpact, 2020 - Elsevier
Cancer, as a global health issue, its treatment with conventional approaches is challenged
by non-specific biodistribution and targeting, poor solubility, low therapeutic indices and …
by non-specific biodistribution and targeting, poor solubility, low therapeutic indices and …
Comprehensive survey on nanobiomaterials for bone tissue engineering applications
One of the most important ideas ever produced by the application of materials science to the
medical field is the notion of biomaterials. The nanostructured biomaterials play a crucial …
medical field is the notion of biomaterials. The nanostructured biomaterials play a crucial …
Dendrimer as a versatile platform for biomedical application: A review
Modern chemistry is vastly fascinated by dendrimer chemistry, an area that is rapidly
expanding and brimming with potential applications. Dendrimers are highly branched …
expanding and brimming with potential applications. Dendrimers are highly branched …
Opportunity in nanomedicine to counter the challenges of current drug delivery approaches used for the treatment of malaria: a review
Malaria is a life-threatening parasitic disease transmitted by the infected female Anopheles
mosquito. The development of drug tolerance and challenges related to the drugs' …
mosquito. The development of drug tolerance and challenges related to the drugs' …
pH-responsive lipid–dendrimer hybrid nanoparticles: An approach to target and eliminate intracellular pathogens
pH-responsive drug delivery systems are yielding opportunities to directly deliver antibiotics
to the site of infection. Therefore, this study aimed to develop and evaluate novel pH …
to the site of infection. Therefore, this study aimed to develop and evaluate novel pH …
Dendrimer-mediated targeted delivery of rapamycin to tumor-associated macrophages improves systemic treatment of glioblastoma
Glioblastoma exhibits high mortality rates due to challenges with drug delivery to the brain
and into solid tumors. This two-pronged barrier necessitates high doses of systemic …
and into solid tumors. This two-pronged barrier necessitates high doses of systemic …
Nanobiomaterials in support of drug delivery related issues
Nanobiomaterials have been widely accepted as potential drug delivery agents over the
past decade. A wide variety of materials have been utilized as drug delivery carriers for …
past decade. A wide variety of materials have been utilized as drug delivery carriers for …
The role of branch cell symmetry and other critical nanoscale design parameters in the determination of dendrimer encapsulation properties
DA Tomalia, LS Nixon, DM Hedstrand - Biomolecules, 2020 - mdpi.com
This article reviews progress over the past three decades related to the role of dendrimer-
based, branch cell symmetry in the development of advanced drug delivery systems …
based, branch cell symmetry in the development of advanced drug delivery systems …