Doxorubicin (DOX) is a chemotherapeutic agent with marked, dose-dependent cardiotoxicity
that leads to tachycardia, atrial and ventricular arrhythmia, and irreversible heart failure …

Cardiovascular disease (CVD) is an important cause of disease-related death worldwide.
One of its main pathological bases is imbalances in gene expression. Non-coding RNAs are …

Abstract Background/Aim Colorectal cancer (CRC), is characterized by aberrant microRNA
(miRNA) expression during their development and progression. Recently, miR-509–5p's …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common critical
diseases. Bone marrow mesenchymal stem cell (BMSC) transplantation is previously shown …

Ferroptosis is a novel form of regulated cell death characterized by accumulated lipid
reactive oxygen species (ROS) and inactivation of glutathione peroxidase 4 (GPX4). The …

Background Dioscin, a steroidal saponin natural product, has various pharmacological
activities, such as anti-inflammatory, antioxidant, lipid-lowering. However, little is known …

To date, proposed therapies and antiviral drugs have been failed to cure coronavirus
disease 2019 (COVID-19) patients. However, at least two drug companies have applied for …

Cardiovascular diseases (CVDs) are the leading cause of deaths worldwide with regulated
cell death playing an important role in cardiac pathophysiology. However, the classical …

Diabetic cardiomyopathy (DCM) is a common complication in patients with diabetes, and
ultimately leads to heart failure. Endoplasmic reticulum stress (ERS) induced by abnormal …

Oxidative stress, defined as the excess production of reactive oxygen species (ROS) relative
to antioxidant defense, plays a significant role in the development of cardiovascular …