AMPA receptors and their minions: auxiliary proteins in AMPA receptor trafficking

D Bissen, F Foss, A Acker-Palmer - Cellular and Molecular Life Sciences, 2019 - Springer
To correctly transfer information, neuronal networks need to continuously adjust their
synaptic strength to extrinsic stimuli. This ability, termed synaptic plasticity, is at the heart of …

New insights into the gene expression associated to amyotrophic lateral sclerosis

D Recabarren-Leiva, M Alarcón - Life sciences, 2018 - Elsevier
Amyotrophic lateral sclerosis (ALS) is the most prevalent neuromuscular disease worldwide.
It is a lethal and progressive neurodegenerative disease, principally affecting motor …

Pubertal development in healthy children is mirrored by DNA methylation patterns in peripheral blood

K Almstrup, M Lindhardt Johansen, AS Busch… - Scientific reports, 2016 - nature.com
Puberty marks numerous physiological processes which are initiated by central activation of
the hypothalamic–pituitary–gonadal axis, followed by development of secondary sexual …

SCG10 is required for peripheral axon maintenance and regeneration in mice

Y Li, Y Tian, X Pei, P Zheng, L Miao, L Li… - Journal of Cell …, 2023 - journals.biologists.com
Proper microtubule dynamics are critical for neuronal morphogenesis and functions, and
their dysregulation results in neurological disorders and regeneration failure. Superior …

Spatial control of membrane traffic in neuronal dendrites

MR Radler, A Suber, ET Spiliotis - Molecular and Cellular Neuroscience, 2020 - Elsevier
Neuronal dendrites are highly branched and specialized compartments with distinct
structures and secretory organelles (eg, spines, Golgi outposts), and a unique cytoskeletal …

Levels of endocrine-disrupting chemicals are associated with changes in the peri-pubertal epigenome

K Almstrup, H Frederiksen… - Endocrine …, 2020 - ec.bioscientifica.com
Puberty marks a transition period, which leads to the attainment of adult sexual maturity.
Timing of puberty is a strongly heritable trait. However, large genetic association studies can …

Myosin VI drives clathrin-mediated AMPA receptor endocytosis to facilitate cerebellar long-term depression

W Wagner, K Lippmann, FF Heisler, KV Gromova… - Cell reports, 2019 - cell.com
Myosin VI is an actin-based cytoskeletal motor implicated in various steps of membrane
trafficking. Here, we investigated whether this myosin is crucial for synaptic function and …

MicroRNA‑138‑5p regulates neural stem cell proliferation and differentiation in vitro by targeting TRIP6 expression

J Wang, J Li, J Yang, L Zhang… - Molecular …, 2017 - spandidos-publications.com
Research on neural stem cells (NSCs) has recently focused on microRNAs (miRNAs), a
class of small non‑coding RNAs that have crucial roles in regulating NSC proliferation and …

TRIP6 functions in brain ciliogenesis

S Shukla, R Haenold, P Urbánek, L Frappart… - Nature …, 2021 - nature.com
TRIP6, a member of the ZYXIN-family of LIM domain proteins, is a focal adhesion
component. Trip6 deletion in the mouse, reported here, reveals a function in the brain …

Formation of aberrant myotubes by myoblasts lacking myosin VI is associated with alterations in the cytoskeleton organization, myoblast adhesion and fusion

L Lehka, M Topolewska, D Wojton, O Karatsai… - Cells, 2020 - mdpi.com
We have previously postulated that unconventional myosin VI (MVI) could be involved in
myoblast differentiation. Here, we addressed the mechanism (s) of its involvement using …