Over the past few decades, RNA sequencing has significantly progressed, becoming a
paramount approach for transcriptome profiling. The revolution from bulk RNA sequencing …

Hippo pathway is a master regulator of development, cell proliferation, stem cell function,
tissue regeneration, homeostasis, and organ size control. Hippo pathway relays signals from …

Ferroptosis is primarily caused by intracellular iron catalytic activity and lipid peroxidation.
The potential interplay between ferroptosis and apoptosis remains poorly understood. Here …

Hematopoietic stem cell (HSC) aging, which is accompanied by reduced self-renewal ability,
impaired homing, myeloid-biased differentiation, and other defects in hematopoietic …

As a biological carrier, exosomes participate in the communication between various kinds of
cells, and can mediate the interactive 'dialogue'between tumor cells and tumor-associated …

B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is characterized by genetic
alterations with high heterogeneity. Precise subtypes with distinct genomic and/or gene …

The rapid advances in high‐throughput sequencing technologies have made it more evident
that epigenetic modifications orchestrate a plethora of complex biological processes. During …

In recent years, scientific data on cancer has expanded, providing potential for a better
understanding of malignancies and improved tailored care. Advances in Artificial …

Lymphoid cells play a critical role in the immune system, which includes three subgroups of
T, B, and NK cells. Recognition of the complexity of the human genetics transcriptome in …

As extracellular vesicles, exosomes are released from most cells to perform cell–cell
communication. Recent studies have shown that exosomes could be released into tumor …