[HTML][HTML] Consensus numbering system for the rifampicin resistance-associated rpoB gene mutations in pathogenic mycobacteria

E André, L Goeminne, A Cabibbe, P Beckert… - Clinical Microbiology …, 2017 - Elsevier
The rpoB gene codes for the RNA polymerase β subunit, which is the target of rifampicin, an
essential drug in the treatment of tuberculosis and other mycobacterial infections. This gene …

[PDF][PDF] Drug-resistant leprosy: monitoring and current status

DL Williams, TP Gillis - Leprosy review, 2012 - leprosyreview.org
Leprosy control depends solely on case detection and treatment with multi-drug therapy
(MDT). 1–3 This strategy is based on the principle that identifying and treating chronic …

[HTML][HTML] Antimicrobial resistance in leprosy: results of the first prospective open survey conducted by a WHO surveillance network for the period 2009–15

E Cambau, P Saunderson, M Matsuoka, ST Cole… - Clinical Microbiology …, 2018 - Elsevier
Objectives Antimicrobial resistance (AMR) is a priority for surveillance in bacterial infections.
For leprosy, AMR has not been assessed because Mycobacterium leprae does not grow in …

Real-time PCR as a diagnostic tool for bacterial diseases

M Maurin - Expert review of molecular diagnostics, 2012 - Taylor & Francis
In recent years, quantitative real-time PCR tests have been extensively developed in clinical
microbiology laboratories for routine diagnosis of infectious diseases, particularly bacterial …

Drug resistance (dapsone, rifampicin, ofloxacin) and resistance-related gene mutation features in leprosy patients: a systematic review and meta-analysis

X Li, G Li, J Yang, G Jin, Y Shao, Y Li, P Wei… - International Journal of …, 2022 - mdpi.com
Dapsone (DDS), Rifampicin (RIF) and Ofloxacin (OFL) are drugs recommended by the
World Health Organization (WHO) for the treatment of leprosy. In the context of leprosy …

Heterozygous single-nucleotide polymorphism genotypes at heat shock protein 70 gene potentially influence thermo-tolerance among four zebu breeds of Nigeria

GO Onasanya, GM Msalya, AK Thiruvenkadan… - Frontiers in …, 2021 - frontiersin.org
Genetic variants at heat shock protein 70 gene and their influence on heat stress (HS)
tolerance were studied among selected Nigeria zebu, namely, 25 White Fulani (WF), 21 …

[HTML][HTML] Tristetraprolin activation by resveratrol inhibits the proliferation and metastasis of colorectal cancer cells

SR Lee, H Jin, WT Kim, WJ Kim… - International …, 2018 - spandidos-publications.com
Resveratrol (RSV) is a polyphenolic compound that naturally occurs in grapes, peanuts and
berries. Considerable research has been conducted to determine the benefits of RSV …

Hi-plex deep amplicon sequencing for identification, high-resolution genotyping and multidrug resistance prediction of Mycobacterium leprae directly from patient …

A Jouet, SM Braet, C Gaudin, G Bisch… - …, 2023 - thelancet.com
Background Expansion of antimicrobial resistance monitoring and epidemiological
surveillance are key components of the WHO strategy towards zero leprosy. The inability to …

Drug resistance patterns in Mycobacterium leprae isolates from relapsed leprosy patients attending The Leprosy Mission (TLM) Hospitals in India

M Lavania, RS Jadhav, VS Chaitanya… - Leprosy …, 2014 - leprosyreview.org
Implementation of multidrug therapy (MDT) in leprosy control programmes has significantly
reduced the global prevalence of the disease in the last two decades. After many years of …

Improving quantitative power in digital PCR through digital high-resolution melting

A Aralar, Y Yuan, K Chen, Y Geng… - Journal of Clinical …, 2020 - Am Soc Microbiol
Applying digital PCR (dPCR) technology to challenging clinical and industrial detection
tasks has become more prevalent because of its capability for absolute quantification and …