Receptor for advanced glycation end products (RAGE): a pivotal hub in immune diseases

Q Yue, Y Song, Z Liu, L Zhang, L Yang, J Li - Molecules, 2022 - mdpi.com
As a critical molecule in the onset and sustainment of inflammatory response, the receptor
for advanced glycation end products (RAGE) has a variety of ligands, such as advanced …

[HTML][HTML] Implications of receptor for advanced glycation end products for progression from obesity to diabetes and from diabetes to cancer

A Garza-Campos, JR Prieto-Correa… - World journal of …, 2023 - ncbi.nlm.nih.gov
Obesity and type 2 diabetes mellitus (T2DM) are chronic pathologies with a high incidence
worldwide. They share some pathological mechanisms, including hyperinsulinemia, the …

The role of soluble receptor for advanced glycation end-products (sRAGE) in the general population and patients with diabetes mellitus with a focus on renal function …

M Steenbeke, S De Bruyne, M De Buyzere… - Critical Reviews in …, 2021 - Taylor & Francis
Isoforms of the receptor for advanced glycation end-product (RAGE) protein, which lack the
transmembrane and the signaling (soluble RAGE or sRAGE) domains are hypothesized to …

[HTML][HTML] Modulation of soluble receptor for advanced glycation end-products (RAGE) isoforms and their ligands in healthy aging

F Scavello, F Zeni, CC Tedesco, E Mensà… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
The receptor for advanced glycation end-products (RAGE) recognizes several ligands
involved in inflammatory diseases. Two circulating soluble isoforms exist: esRAGE derived …

Soluble RAGE and skeletal muscle tissue RAGE expression profiles in lean and obese young adults across differential aerobic exercise intensities

ER Miranda, JT Mey, BK Blackburn… - Journal of Applied …, 2023 - journals.physiology.org
Nearly 40% of Americans have obesity and are at increased risk for developing type 2
diabetes. Skeletal muscle is responsible for> 80% of insulin-stimulated glucose uptake that …

Blood and tissue advanced glycation end products as determinants of cardiometabolic disorders focusing on human studies

Y Kim - Nutrients, 2023 - mdpi.com
Cardiometabolic disorders are characterised by a cluster of interactive risk determinants
such as increases in blood glucose, lipids and body weight, as well as elevated …

Advanced glycation end products (AGEs) and their soluble receptors (sRAGE) as early predictors of reno-vascular complications in patients with uncontrolled type 2 …

SS Farhan, SA Hussain - … & Metabolic Syndrome: Clinical Research & …, 2019 - Elsevier
Aim To evaluate the role of advanced glycation end-products (AGEs) and their soluble
receptors (sRAGE) expression levels as predictors of vascular complications in uncontrolled …

Obesity and comorbidity: could simultaneous targeting of esRAGE and sRAGE be the panacea?

C Eleazu, N Omar, OZ Lim, BS Yeoh… - Frontiers in …, 2019 - frontiersin.org
Obesity, a chronic multifaceted disease, predisposes its patients to increased risk of
metabolic disorders such as: diabetes mellitus, cardiovascular diseases, dyslipidemia, etc …

Polymorphisms− 374 T/A and− 429 T/C of the receptor for advanced glycation end-products (RAGE) and serum levels of RAGE (sRAGE) are not associated with …

DE González-Guerrero, ML Lazo-de-la-Vega-Monroy… - Metabolites, 2023 - mdpi.com
RAGE is a multi-ligand transmembrane glycoprotein that promotes biological signals
associated with inflammatory responses and degenerative diseases. sRAGE is a soluble …

Soluble receptor for advanced glycation end products (sRAGE) is associated with obesity rates: a systematic review and meta-analysis of cross-sectional study

NA Tayyib, P Ramaiah, SH Alshahrani… - BMC Endocrine …, 2023 - Springer
Background Several studies have highlighted the possible positive effects of soluble
receptor for advanced glycation end products (sRAGE) against obesity. However, due to …