[HTML][HTML] Insights into aldehyde dehydrogenase enzymes: a structural perspective

K Shortall, A Djeghader, E Magner… - Frontiers in Molecular …, 2021 - frontiersin.org
Aldehyde dehydrogenases engage in many cellular functions, however their dysfunction
resulting in accumulation of their substrates can be cytotoxic. ALDHs are responsible for the …

Aldehyde toxicity and metabolism: the role of aldehyde dehydrogenases in detoxification, drug resistance and carcinogenesis

A Ahmed Laskar, H Younus - Drug metabolism reviews, 2019 - Taylor & Francis
Aldehydes are carbonyl compounds found ubiquitously in the environment, derived from
both natural and anthropogenic sources. As the aldehydes are reactive species, therefore …

[HTML][HTML] Tandem gene duplications drive divergent evolution of caffeine and crocin biosynthetic pathways in plants

Z Xu, X Pu, R Gao, OC Demurtas, SJ Fleck, M Richter… - BMC biology, 2020 - Springer
Background Plants have evolved a panoply of specialized metabolites that increase their
environmental fitness. Two examples are caffeine, a purine psychotropic alkaloid, and …

[HTML][HTML] Reactive carbonyl species: a missing link in ROS signaling

J Mano, MS Biswas, K Sugimoto - Plants, 2019 - mdpi.com
As reactive oxygen species (ROS) play critical roles in plants to determine cell fate in various
physiological situations, there is keen interest in the biochemical processes of ROS signal …

[HTML][HTML] Indole-3-acetaldehyde dehydrogenase-dependent auxin synthesis contributes to virulence of Pseudomonas syringae strain DC3000

SA McClerklin, SG Lee, CP Harper, R Nwumeh… - PLoS …, 2018 - journals.plos.org
The bacterial pathogen Pseudomonas syringae modulates plant hormone signaling to
promote infection and disease development. P. syringae uses several strategies to …

[HTML][HTML] Dynamic metabolic profiling together with transcription analysis reveals salinity-induced starch-to-lipid biosynthesis in alga Chlamydomonas sp. JSC4

SH Ho, A Nakanishi, Y Kato, H Yamasaki, JS Chang… - Scientific reports, 2017 - nature.com
Biodiesel production using microalgae would play a pivotal role in satisfying future global
energy demands. Understanding of lipid metabolism in microalgae is important to isolate …

The JA‐responsive MYC2‐BADHlike transcriptional regulatory module in Poncirus trifoliata contributes to cold tolerance by modulation of glycine betaine …

R Ming, Y Zhang, Y Wang, M Khan, B Dahro… - New …, 2021 - Wiley Online Library
Glycine betaine (GB) is known to accumulate in plants exposed to cold, but the underlying
molecular mechanisms and associated regulatory network remain unclear. Here, we …

[HTML][HTML] Novel insights into host-pathogen interactions of large yellow croakers (Larimichthys crocea) and pathogenic bacterium Pseudomonas plecoglossicida using …

Y Tang, G Xin, LM Zhao, LX Huang, YX Qin… - Zoological …, 2020 - ncbi.nlm.nih.gov
Host-pathogen interactions are highly complex, involving large dynamic changes in gene
expression during infection. These interactions are fundamental to understanding anti …

Aldehyde dehydrogenases: from eye crystallins to metabolic disease and cancer stem cells

V Vasiliou, DC Thompson, C Smith, M Fujita… - Chemico-biological …, 2013 - Elsevier
The aldehyde dehydrogenase (ALDH) superfamily is composed of nicotinamide adenine
dinucleotide (phosphate)(NAD (P)+)-dependent enzymes that catalyze the oxidation of …

[HTML][HTML] Recent development on plant aldehyde dehydrogenase enzymes and their functions in plant development and stress signaling

AJ Tola, A Jaballi, H Germain, TD Missihoun - Genes, 2020 - mdpi.com
Abiotic and biotic stresses induce the formation of reactive oxygen species (ROS), which
subsequently causes the excessive accumulation of aldehydes in cells. Stress-derived …