Neuronal dysfunction and gene modulation by non-coding RNA in Parkinson's disease and synucleinopathies

R Meccariello, GC Bellenchi, S Pulcrano… - Frontiers in Cellular …, 2024 - frontiersin.org
Over the last few decades, emerging evidence suggests that non-coding RNAs (ncRNAs)
including long-non-coding RNA (lncRNA), microRNA (miRNA) and circular-RNA (circRNA) …

Glial populations in the human brain following ischemic injury

V Mihailova, II Stoyanova, AB Tonchev - Biomedicines, 2023 - mdpi.com
There is a growing interest in glial cells in the central nervous system due to their important
role in maintaining brain homeostasis under physiological conditions and after injury. A …

Single-cell epigenome analysis identifies molecular events controlling direct conversion of human fibroblasts to pancreatic ductal-like cells

L Fei, K Zhang, N Poddar, S Hautaniemi, B Sahu - Developmental Cell, 2023 - cell.com
Cell fate can be reprogrammed by ectopic expression of lineage-specific transcription
factors (TFs). However, the exact cell state transitions during transdifferentiation are still …

Direct conversion of human fibroblasts to pancreatic epithelial cells through transient progenitor states is controlled by temporal activation of defined factors

L Fei, K Zhang, N Poddar, S Hautaniemi, B Sahu - bioRxiv, 2022 - biorxiv.org
Cell fate can be reprogrammed by ectopic expression of lineage-specific transcription
factors (TF). For example, few specialized cell types like neurons, hepatocytes and …