[HTML][HTML] Bioavailability enhancement techniques for poorly aqueous soluble drugs and therapeutics

DV Bhalani, B Nutan, A Kumar, AK Singh Chandel - Biomedicines, 2022 - mdpi.com
The low water solubility of pharmacoactive molecules limits their pharmacological potential,
but the solubility parameter cannot compromise, and so different approaches are employed …

[HTML][HTML] Advances in oral drug delivery

MS Alqahtani, M Kazi, MA Alsenaidy… - Frontiers in …, 2021 - frontiersin.org
The oral route is the most common route for drug administration. It is the most preferred
route, due to its advantages, such as non-invasiveness, patient compliance and …

[HTML][HTML] Nanotechnology: a promising approach for delivery of neuroprotective drugs

S Naqvi, A Panghal, SJS Flora - Frontiers in Neuroscience, 2020 - frontiersin.org
Central nervous system (CNS) disorders especially neurodegenerative disorders are the
major challenge for public health and demand the great attention of researchers to protect …

[HTML][HTML] Intestinal absorption study: Challenges and absorption enhancement strategies in improving oral drug delivery

M Azman, AH Sabri, QK Anjani, MF Mustaffa… - Pharmaceuticals, 2022 - mdpi.com
The oral route is the most common and practical means of drug administration, particularly
from a patient's perspective. However, the pharmacokinetic profile of oral drugs depends on …

[HTML][HTML] Emerging innate biological properties of nano-drug delivery systems: A focus on PAMAM dendrimers and their clinical potential

H Kheraldine, O Rachid, AM Habib… - Advanced drug delivery …, 2021 - Elsevier
Drug delivery systems or vectors are usually needed to improve the bioavailability and
effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an …

[HTML][HTML] Pharmaceutical formulations with P-glycoprotein inhibitory effect as promising approaches for enhancing oral drug absorption and bioavailability

TTL Nguyen, VA Duong, HJ Maeng - Pharmaceutics, 2021 - mdpi.com
P-glycoprotein (P-gp) is crucial in the active transport of various substrates with diverse
structures out of cells, resulting in poor intestinal permeation and limited bioavailability …

[HTML][HTML] New advances in general biomedical applications of PAMAM dendrimers

RV Araújo, SS Santos, E Igne Ferreira, J Giarolla - Molecules, 2018 - mdpi.com
Dendrimers are nanoscopic compounds, which are monodispersed, and they are generally
considered as homogeneous. PAMAM (polyamidoamine) was introduced in 1985, by …

[HTML][HTML] Oral delivery of protein and peptide drugs: From non-specific formulation approaches to intestinal cell targeting strategies

G Chen, W Kang, W Li, S Chen, Y Gao - Theranostics, 2022 - ncbi.nlm.nih.gov
The past few years has witnessed a booming market of protein and peptide drugs, owing to
their superior efficiency and biocompatibility. Parenteral route is the most commonly …

Nanotechnological carriers for cancer chemotherapy: the state of the art

M Estanqueiro, MH Amaral, J Conceição… - Colloids and surfaces B …, 2015 - Elsevier
Cancer is a term used for a heterogeneous group of malignant diseases in which abnormal
cells divide without control and are able to invade other tissues, resulting in metastasis …

[HTML][HTML] Review on PLGA polymer based nanoparticles with antimicrobial properties and their application in various medical conditions or infections

AK Shakya, M Al-Sulaibi, RR Naik, H Nsairat, S Suboh… - Polymers, 2023 - mdpi.com
The rise in the resistance to antibiotics is due to their inappropriate use and the use of a
broad spectrum of antibiotics. This has also contributed to the development of multidrug …