[HTML][HTML] Bioavailability enhancement techniques for poorly aqueous soluble drugs and therapeutics
The low water solubility of pharmacoactive molecules limits their pharmacological potential,
but the solubility parameter cannot compromise, and so different approaches are employed …
but the solubility parameter cannot compromise, and so different approaches are employed …
[HTML][HTML] Advances in oral drug delivery
The oral route is the most common route for drug administration. It is the most preferred
route, due to its advantages, such as non-invasiveness, patient compliance and …
route, due to its advantages, such as non-invasiveness, patient compliance and …
[HTML][HTML] Nanotechnology: a promising approach for delivery of neuroprotective drugs
Central nervous system (CNS) disorders especially neurodegenerative disorders are the
major challenge for public health and demand the great attention of researchers to protect …
major challenge for public health and demand the great attention of researchers to protect …
[HTML][HTML] Intestinal absorption study: Challenges and absorption enhancement strategies in improving oral drug delivery
M Azman, AH Sabri, QK Anjani, MF Mustaffa… - Pharmaceuticals, 2022 - mdpi.com
The oral route is the most common and practical means of drug administration, particularly
from a patient's perspective. However, the pharmacokinetic profile of oral drugs depends on …
from a patient's perspective. However, the pharmacokinetic profile of oral drugs depends on …
[HTML][HTML] Emerging innate biological properties of nano-drug delivery systems: A focus on PAMAM dendrimers and their clinical potential
Drug delivery systems or vectors are usually needed to improve the bioavailability and
effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an …
effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an …
[HTML][HTML] Pharmaceutical formulations with P-glycoprotein inhibitory effect as promising approaches for enhancing oral drug absorption and bioavailability
P-glycoprotein (P-gp) is crucial in the active transport of various substrates with diverse
structures out of cells, resulting in poor intestinal permeation and limited bioavailability …
structures out of cells, resulting in poor intestinal permeation and limited bioavailability …
[HTML][HTML] New advances in general biomedical applications of PAMAM dendrimers
Dendrimers are nanoscopic compounds, which are monodispersed, and they are generally
considered as homogeneous. PAMAM (polyamidoamine) was introduced in 1985, by …
considered as homogeneous. PAMAM (polyamidoamine) was introduced in 1985, by …
[HTML][HTML] Oral delivery of protein and peptide drugs: From non-specific formulation approaches to intestinal cell targeting strategies
G Chen, W Kang, W Li, S Chen, Y Gao - Theranostics, 2022 - ncbi.nlm.nih.gov
The past few years has witnessed a booming market of protein and peptide drugs, owing to
their superior efficiency and biocompatibility. Parenteral route is the most commonly …
their superior efficiency and biocompatibility. Parenteral route is the most commonly …
Nanotechnological carriers for cancer chemotherapy: the state of the art
M Estanqueiro, MH Amaral, J Conceição… - Colloids and surfaces B …, 2015 - Elsevier
Cancer is a term used for a heterogeneous group of malignant diseases in which abnormal
cells divide without control and are able to invade other tissues, resulting in metastasis …
cells divide without control and are able to invade other tissues, resulting in metastasis …
[HTML][HTML] Review on PLGA polymer based nanoparticles with antimicrobial properties and their application in various medical conditions or infections
The rise in the resistance to antibiotics is due to their inappropriate use and the use of a
broad spectrum of antibiotics. This has also contributed to the development of multidrug …
broad spectrum of antibiotics. This has also contributed to the development of multidrug …