β-lactamases (BLs) represent the most frequent cause of antimicrobial resistance in Gram-
negative bacteria. Despite the continuous efforts in the development of BL inhibitors (BLIs) …

The spread of the Dengue virus over the world, as well as multiple outbreaks of different
serotypes, has resulted in a large number of deaths and a medical emergency, as no viable …

Antimicrobial resistance is a global threat. The use of biologically active natural products
alone or in combination with the clinically proven antimicrobial agents might be a useful …

TEM family of enzymes is one of the most commonly encountered β-lactamases groups with
different catalytic capabilities against various antibiotics. Despite the studies investigating …

Abstract β-Lactams are the most effective antibiotics for the treatment of infectious diseases.
Unfortunately, the bacterial β-lactamase breaks down the β-lactam ring, and hence …

Для защиты беталактамных антибиотиков от действия резистентных бактерий
используются ингибиторы β-лактамаз. Однако из-за появления устойчивости к β …

Objectives: β-Lactams are the most successful antibiotics for the management of infectious
diseases. Unfortunately, the bacterial production of β-lactamase that hydrolyzes the β-lactam …

ABSTRACT β-lactam antibiotics have become the standard treatment for bacterial infections.
Production of β-lactamases as the major cause of bacterial resistance inactivates the β …

A Beta-Lactamase Inhibitor Identified Rough Virtual Screening Page 44 -35- A Beta-Lactamase
Inhibitor Identified Rough Virtual Screening İklima ZÜNBÜL, Ebru ÇAKA, Yusuf Ceyhun …

Selen Şenal is an entrepreneurial bioengineer well-experienced in process design,
synthetic biology, reactor engineering, renewable energy, and climate change. She is a …