Stroke is one of the main causes of mortality and disability in most countries of the world.
The only way of managing patients with ischemic stroke is the use of intravenous tissue …

Tibolone (TIB), a selective tissue estrogenic activity regulator (STEAR) in clinical use by
postmenopausal women, activates hormonal receptors in a tissue-specific manner …

Cerebral ischemia-reperfusion (I/R) injury is a key contributing factor to the pathogenic
mechanisms involved in ischemic stroke. The present study was designed to explore the …

Although the neuroprotective effects of calcitriol have been demonstrated in a variety of
neurological diseases, such as stroke, the precise molecular mechanism has yet to be …

Objectives The mechanisms responsible for the postnatal loss of mammalian cardiac
regenerative capacity are not fully elucidated. The aim of the present study is to investigate …

Sustained activation of pro-apoptotic signaling due to a sudden and prolonged disturbance
of cerebral blood circulation governs the neurodegenerative processes in prefrontal cortex …

Progesterone plays a crucial and indispensable role in regulating immunity and attenuating
inflammation. Nestorone®(NES, segesterone acetate) is a steroidal progestin and a 19 …

The ovaries are an important component of the female reproductive system, whose main
purpose is to produce mature oocytes. They also function as endocrine glands, secreting …

Background As a promising way to repair bone defect, bone tissue engineering has
attracted a lot of attentions from researchers in recent years. Searching for new molecular …

Stroke is a prominent and consequential factor contributing to mortality and disability. Both
biological sex and sociocultural gender exert an influence on stroke risk factors …