Lyme borreliosis

AC Steere, F Strle, GP Wormser, LT Hu… - Nature reviews Disease …, 2016 - nature.com
Lyme borreliosis is a tick-borne disease that predominantly occurs in temperate regions of
the northern hemisphere and is primarily caused by the bacterium Borrelia burgdorferi in …

Interactions between Borrelia burgdorferi and ticks

C Kurokawa, GE Lynn, JHF Pedra, U Pal… - Nature Reviews …, 2020 - nature.com
Borrelia burgdorferi is the causative agent of Lyme disease and is transmitted to vertebrate
hosts by Ixodes spp. ticks. The spirochaete relies heavily on its arthropod host for basic …

mRNA vaccination induces tick resistance and prevents transmission of the Lyme disease agent

A Sajid, J Matias, G Arora, C Kurokawa… - Science translational …, 2021 - science.org
Ixodes scapularis ticks transmit many pathogens that cause human disease, including
Borrelia burgdorferi. Acquired resistance to I. scapularis due to repeated tick exposure has …

Tick-pathogen interactions and vector competence: identification of molecular drivers for tick-borne diseases

J De la Fuente, S Antunes, S Bonnet… - Frontiers in cellular …, 2017 - frontiersin.org
Ticks and the pathogens they transmit constitute a growing burden for human and animal
health worldwide. Vector competence is a component of vectorial capacity and depends on …

Lyme disease in humans

JD Radolf, K Strle, JE Lemieux, F Strle - Current issues in molecular …, 2021 - mdpi.com
Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …

The essential role of tick salivary glands and saliva in tick feeding and pathogen transmission

L Šimo, M Kazimirova, J Richardson… - Frontiers in cellular and …, 2017 - frontiersin.org
As long-term pool feeders, ticks have developed myriad strategies to remain discreetly but
solidly attached to their hosts for the duration of their blood meal. The critical biological …

Lyme disease pathogenesis

J Coburn, B Garcia, LT Hu, MW Jewett… - Current issues in …, 2021 - mdpi.com
Lyme disease Borrelia are obligately parasitic, tick-transmitted, invasive, persistent bacterial
pathogens that cause disease in humans and non-reservoir vertebrates primarily through …

Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes

JD Radolf, MJ Caimano, B Stevenson… - Nature reviews …, 2012 - nature.com
In little more than 30 years, Lyme disease, which is caused by the spirochaete Borrelia
burgdorferi, has risen from relative obscurity to become a global public health problem and a …

West Nile Virus: biology, transmission, and human infection

TM Colpitts, MJ Conway… - Clinical microbiology …, 2012 - Am Soc Microbiol
SUMMARY West Nile Virus was introduced into the Western Hemisphere during the late
summer of 1999 and has been causing significant and sometimes severe human diseases …

The evolving story of Borrelia burgdorferi sensu lato transmission in Europe

A Steinbrink, K Brugger, G Margos, P Kraiczy… - Parasitology …, 2022 - Springer
Beside mosquitoes, ticks are well-known vectors of different human pathogens. In the
Northern Hemisphere, Lyme borreliosis (Eurasia, LB) or Lyme disease (North America, LD) …