Signal amplification by reversible exchange (SABRE) is a rapidly developing nuclear
magnetic resonance (NMR) hyperpolarization technique utilizing parahydrogen for dramatic …

Signal amplification by reversible exchange (SABRE) creates “hyperpolarization”(large spin
magnetization) using a transition metal catalyst and parahydrogen, addressing the …

The inherently low signal-to-noise ratio of NMR and MRI is now being addressed by
hyperpolarization methods. For example, iridium-based catalysts that reversibly bind both …

SABRE (Signal Amplification by Reversible Exchange) methods provide a simple, fast, and
cost-effective method to hyperpolarize a wide variety of molecules in solution, and have …

Parahydrogen (pH2) is a convenient and cost‐efficient source of spin order to enhance the
magnetic resonance signal. Previous work showed that transient interaction of pH2 with a …

Hyperpolarization methods in magnetic resonance overcome sensitivity limitations,
especially for low-γ nuclei such as 13C and 15N. Signal Amplification By Reversible …

Dissolution dynamic nuclear polarization (dDNP) is a method of choice for preparing
hyperpolarized 13C metabolites such as 1-13C-pyruvate used for in vivo applications …

Abstract Signal Amplification By Reversible Exchange (SABRE) and the heteronuclear
variant, X-SABRE, increase the sensitivity of magnetic resonance techniques using order …

Purpose Despite significant impact on the study of human brain, MRI lacks a theory of signal
formation that integrates quantum interactions involving proton dipoles (a primary MRI signal …

The inherently low signal-to-noise ratio of NMR and MRI is now being addressed by
hyperpolarization methods. For example, iridium-based catalysts that reversibly bind both …