Physical principles of nanoparticle cellular endocytosis
This review article focuses on the physiochemical mechanisms underlying nanoparticle
uptake into cells. When nanoparticles are in close vicinity to a cell, the interactions between …
uptake into cells. When nanoparticles are in close vicinity to a cell, the interactions between …
Entry of nanoparticles into cells: The importance of nanoparticle properties
J Zhao, MH Stenzel - Polymer Chemistry, 2018 - pubs.rsc.org
Knowledge of the interactions between nanoparticles (NPs) and cell membranes is of great
importance for the design of safe and efficient nanomedicines. Extensive studies aimed at …
importance for the design of safe and efficient nanomedicines. Extensive studies aimed at …
Perspective: Dissipative particle dynamics
Dissipative particle dynamics (DPD) belongs to a class of models and computational
algorithms developed to address mesoscale problems in complex fluids and soft matter in …
algorithms developed to address mesoscale problems in complex fluids and soft matter in …
Engineered strategies to enhance tumor penetration of drug-loaded nanoparticles
Nanocarriers have been widely employed in preclinical studies and clinical trials for the
delivery of anticancer drugs. The most important causes of failure in clinical translation of …
delivery of anticancer drugs. The most important causes of failure in clinical translation of …
Converting nanotoxicity data to information using artificial intelligence and simulation
Decades of nanotoxicology research have generated extensive and diverse data sets.
However, data is not equal to information. The question is how to extract critical information …
However, data is not equal to information. The question is how to extract critical information …
[HTML][HTML] Towards principled design of cancer nanomedicine to accelerate clinical translation
Nanotechnology in medical applications, especially in oncology as drug delivery systems,
has recently shown promising results. However, although these advances have been …
has recently shown promising results. However, although these advances have been …
[HTML][HTML] Exploration and insights into the cellular internalization and intracellular fate of amphiphilic polymeric nanocarriers
The beneficial or deleterious effects of nanomedicines emerge from their complex
interactions with intracellular pathways and their subcellular fate. Moreover, the dynamic …
interactions with intracellular pathways and their subcellular fate. Moreover, the dynamic …
In Silico Study of Gold Nanoparticle Uptake into a Mammalian Cell: Interplay of Size, Shape, Surface Charge, and Aggregation
T Lunnoo, J Assawakhajornsak… - The Journal of Physical …, 2019 - ACS Publications
The study of interactions between Au nanostructures and living cells is a fundamental aspect
that can be applied for promising applications in nanomedicine. In the present work, we …
that can be applied for promising applications in nanomedicine. In the present work, we …
Permeation of nanoparticles across the intestinal lipid membrane: dependence on shape and surface chemistry studied through molecular simulations
Nanoparticles are being explored for topical and oral drug delivery applications as they can
cross various biological barriers, for example, the intestinal epithelium. The ability of …
cross various biological barriers, for example, the intestinal epithelium. The ability of …
Graphene quantum dot assisted translocation of drugs into a cell membrane
Graphene quantum dots (GQDs) are increasingly being recognized as anti-cancer drug
carriers, eg, doxorubicin delivery, in many experiments. In this work, the structure …
carriers, eg, doxorubicin delivery, in many experiments. In this work, the structure …