Beyond gel electrophoresis: Microfluidic separations, fluorescence burst analysis, and DNA stretching

KD Dorfman, SB King, DW Olson, JDP Thomas… - Chemical …, 2013 - ACS Publications
This Review addresses methods for obtaining sequence information directly from
unamplified genomic length DNA. Our generic starting point is a large piece of DNA that …

DNA electrophoresis in microfabricated devices

KD Dorfman - Reviews of Modern Physics, 2010 - APS
Picking up at the conclusion of Viovy's review of the physics of gel electrophoresis [J.-L.
Viovy, Rev. Mod. Phys. 72, 813 (2000) 10.1103/RevModPhys. 72.813], this review …

Electrostatic focusing of unlabelled DNA into nanoscale pores using a salt gradient

M Wanunu, W Morrison, Y Rabin, AY Grosberg… - Nature …, 2010 - nature.com
Solid-state nanopores are sensors capable of analysing individual unlabelled DNA
molecules in solution. Although the critical information obtained from nanopores (for …

[图书][B] Polymer translocation

M Muthukumar - 2016 - books.google.com
A reflection of the significant advances in the field, this book discusses the macromolecular
basis of polymer translocation that have emerged based on experimentation, new models …

Rapid sequencing of individual DNA molecules in graphene nanogaps

HWC Postma - Nano letters, 2010 - ACS Publications
I propose a technique for reading the base sequence of a single DNA molecule using a
graphene nanogap to read the DNA's transverse conductance. Because graphene is a …

Fabrication and microfluidic analysis of graphene-based molecular communication receiver for Internet of Nano Things (IoNT)

M Kuscu, H Ramezani, E Dinc, S Akhavan, OB Akan - Scientific reports, 2021 - nature.com
Bio-inspired molecular communications (MC), where molecules are used to transfer
information, is the most promising technique to realise the Internet of Nano Things (IoNT) …

An experimentally-informed coarse-grained 3-site-per-nucleotide model of DNA: Structure, thermodynamics, and dynamics of hybridization

DM Hinckley, GS Freeman, JK Whitmer… - The Journal of chemical …, 2013 - pubs.aip.org
A new 3-Site-Per-Nucleotide coarse-grained model for DNA is presented. The model
includes anisotropic potentials between bases involved in base stacking and base pair …

Probing single DNA molecule transport using fabricated nanopores

P Chen, J Gu, E Brandin, YR Kim, Q Wang… - Nano …, 2004 - ACS Publications
Nanopores can serve as high throughput, single-molecule sensing devices that provide
insight into the distribution of static and dynamic molecular activities, properties, or …

Recapturing and trapping single molecules with a solid-state nanopore

M Gershow, JA Golovchenko - Nature nanotechnology, 2007 - nature.com
The development of solid-state nanopores,,,,,,, inspired by their biological counterparts,,,,,,,,
shows great potential for the study of single macromolecules,,,,,. Applications such as DNA …

Electrokinetics in micro devices for biotechnology applications

PK Wong, TH Wang, JH Deval… - IEEE/ASME transactions …, 2004 - ieeexplore.ieee.org
Electrokinetics is the study of the motion of bulk fluids or selected particles embedded in
fluids when they are subjected to electric fields. With the recent developments in …