Although cancer is a genetic disease, physical changes such as stiffening of the
extracellular matrix also commonly occur in cancer. Cancer cells sense and respond to …

Treatment strategies targeting programed cell death 1 (PD-1) or its ligand, PD-L1, have
been developed as immunotherapy against tumor progression for various cancer types …

Background Metastasis is a crucial aspect of disease progression leading to death in
patients with prostate cancer (PCa). However, its mechanism remains unclear. We aimed to …

Background Microglia is the major contributor of post-stroke neuroinflammation cascade and
the crucial cellular target for the treatment of ischemic stroke. Currently, the endogenous …

Simple Summary We previously reported a novel mechanism of NRF2 tumoral immune
suppression through selective upregulation of the tryptophan-metabolizing enzyme …

Background Overexpression of the tripartite motif containing 6 (TRIM6) is associated with
dismal prognosis in cancer patients, but its exact roles in lung adenocarcinoma (LUAD) …

Background We aimed to identify the relationship between thyroid transcription factor‐1 (TTF‐
1) expression of lung adenocarcinoma and the efficacy of immune‐checkpoint inhibitor (ICI) …

Abstract Background Cancer-associated fibroblasts (CAFs)-derived IL-8 plays important
roles in chemoresistance, immunosuppression, and lymph node metastasis of gastric …

Background Thyroid transcription factor-1 (TTF-1) is expressed in approximately 70% of lung
adenocarcinomas and is one of the most reliable makers to distinguish primary lung …

GLI1-rearranged mesenchymal tumor in the ovary GLI1-rearranged mesenchymal tumor in the
ovary Histopathology. 2022 Nov;81(5):688-692. doi: 10.1111/his.14785. Epub 2022 Sep 7 …