High-throughput evolution of near-infrared serotonin nanosensors

S Jeong, D Yang, AG Beyene… - Science …, 2019 - science.org
Imaging neuromodulation with synthetic probes is an emerging technology for studying
neurotransmission. However, most synthetic probes are developed through conjugation of …

Tuning selectivity of fluorescent carbon nanotube-based neurotransmitter sensors

FA Mann, N Herrmann, D Meyer, S Kruss - Sensors, 2017 - mdpi.com
Detection of neurotransmitters is an analytical challenge and essential to understand
neuronal networks in the brain and associated diseases. However, most methods do not …

Advances in nanomaterials for brain microscopy

JT Del Bonis-O'Donnell, L Chio, GF Dorlhiac… - Nano research, 2018 - Springer
Microscopic imaging of the brain continues to reveal details of its structure, connectivity, and
function. To further improve our understanding of the emergent properties and functions of …

Electrostatic assemblies of single-walled carbon nanotubes and sequence-tunable peptoid polymers detect a lectin protein and its target sugars

L Chio, JT Del Bonis-O'Donnell, MA Kline, JH Kim… - Nano Letters, 2019 - ACS Publications
A primary limitation to real-time imaging of metabolites and proteins has been the selective
detection of biomolecules that have no naturally occurring or stable molecular recognition …

[图书][B] On Protein Corona Formation: Understanding Nano-Bio Interactions Toward Engineering Optical Nanomaterials

RL Pinals - 2021 - search.proquest.com
Engineered nanoparticles have emerged as a promising platform upon which to develop
biological sensing, imaging, and delivery tools. Yet, a paramount challenge toward …

Development of Single-Walled Carbon Nanotube Protein Optical Nanosensors

L Chio - 2020 - escholarship.org
Many diseases, such as neurodegenerative disorders, cancer, and autoimmune diseases
are caused by or exhibit symptoms of abnormal regulation of signaling proteins. In order to …

Synthetic probe development for measuring single or few-cell activity and efflux

A Lui, J Wang, L Chio, MP Landry - Methods in enzymology, 2019 - Elsevier
Studying the single cell protein secretome offers the opportunity to understand how a
phenotypically heterogeneous population of individual cells contribute to ensemble …