Purpose We performed a systematic review and meta-analysis of available literature to
investigate the efficacy of the intracytoplasmic sperm injection (ICSI) in couples with non …

Intracytoplasmic sperm injection (ICSI) was originally designed to overcome barriers due to
male factor infertility. However, a surveillance study found that ICSI use in non-male factor …

Background The use of intracytoplasmic sperm injection has increased substantially
worldwide, primarily in couples with non-male factor infertility. However, there is a paucity of …

Objective To study how the choice of the first assisted reproductive technology treatment
type affects the cumulative live birth rate (CLBR) in couples with high sperm DNA …

Abstract STUDY QUESTION Are phospholipase C zeta 1 (PLCZ1) mutations associated with
fertilization failure (FF) after ICSI? SUMMARY ANSWER New mutations in the PLCZ1 …

Abstract STUDY QUESTION Do the Comet parameters of the proportions of sperm with low
or high DNA damage improve the power of the test in the diagnosis of male infertility and/or …

STUDY QUESTION Are there more de novo mutations (DNMs) present in the genomes of
children born through medical assisted reproduction (MAR) compared to spontaneously …

STUDY QUESTION Does the insemination method impact the euploidy outcome in couples
with non-male factor infertility? SUMMARY ANSWER Conventional IVF can be applied in …

STUDY QUESTION Does the method of fertilisation improve reproductive outcomes in poor
ovarian response (POR) cycles when compared to all other ovarian response categories in …

Background: Assisted reproductive techniques services are often not accessible to the
majority of infertile couples in Low and Middle Income Countries (LMIC) due to high costs …