Inflammation has been linked to multiple degenerative and acute diseases as well as the
aging process. Moreover, mitochondrial alterations play a central role in these processes …

Simple Summary Recent research suggests a strong link between the functioning of
mitochondria and the development of cancer. Healthy mitochondria play a vital role in …

Humans are inevitably exposed to ethyl carbamate (EC) via consumption of fermented food
and beverages. EC, known as an environmental toxin, can cause oxidative stress-mediated …

To clarify the role of mitochondrial electron transport chain (mtETC) in heavy‐metal‐induced
neurotoxicity, we studied action of Cd2+, Hg2+, and Cu2+ on cell viability, intracellular …

Post-traumatic stress disorder (PTSD) is one of the most discussed and actively researched
areas in medicine, psychiatry, neurophysiology, biochemistry and rehabilitation over the last …

Abstract Lamellarin D (Lam D), a marine alkaloid, exhibits a potent cytotoxicity against many
different tumors. The pro-apoptotic function of Lam D has been attributed to its direct …

Objective Mitochondrial alterations play a key role in the pathogenesis of osteoarthritis (OA).
This study evaluated a potential role of mitochondrial respiratory chain (MRC) dysfunction in …

Conventional genotoxic anti-cancer drugs target the proliferative advantage of tumor cells
over normal cells. This kind of approach lacks the selectivity of treatment to cancer cells …

Despite the introduction of therapeutic hypothermia, neonatal hypoxic ischemic (HI) brain
injury remains a common cause of developmental disability. Development of rational …

Reactive oxygen species (ROS), such as superoxide (O2•-) and hydrogen peroxide (H2O2),
have been reported to be important mediators of the apoptosis induced by death ligands …