Haptoglobin treatment for aneurysmal subarachnoid hemorrhage: review and expert consensus on clinical translation

I Galea, S Bandyopadhyay, D Bulters, R Humar… - Stroke, 2023 - Am Heart Assoc
Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating form of stroke frequently
affecting young to middle-aged adults, with an unmet need to improve outcome. This special …

[HTML][HTML] Double-edged functions of hemopexin in hematological related diseases: from basic mechanisms to clinical application

Y Li, R Chen, C Wang, J Deng, S Luo - Frontiers in Immunology, 2023 - frontiersin.org
It is now understood that hemolysis and the subsequent release of heme into circulation play
a critical role in driving the progression of various diseases. Hemopexin (HPX), a heme …

Red Blood Cells in the Cerebrospinal Fluid Compartment After Subarachnoid Haemorrhage: Significance and Emerging Therapeutic Strategies

S Bandyopadhyay, N Schwendinger… - Translational Stroke …, 2024 - Springer
Subarachnoid haemorrhage (SAH) is a subtype of stroke that predominantly impacts
younger individuals. It is associated with high mortality rates and can cause long-term …

[HTML][HTML] Clinical potential of automated convolutional neural network-based hematoma volumetry after aneurysmal subarachnoid hemorrhage

BR Thomson, F Gürlek, RM Buzzi… - Journal of Stroke and …, 2023 - Elsevier
Objectives Cerebrospinal fluid hemoglobin has been positioned as a potential biomarker
and drug target for aneurysmal subarachnoid hemorrhage-related secondary brain injury …