Mitochondria participate in crucial cellular processes such as energy harvesting and
intermediate metabolism. Although mitochondria possess their own genome—a vestige of …

Mitochondria are one of the most important organelles in cells. Mitochondria are semi-
autonomous organelles with their own genetic system, and can independently replicate …

Mitochondrial unfolded protein response (UPR mt) is a mitochondria stress response, which
the transcriptional activation programs of mitochondrial chaperone proteins and proteases …

Mitochondria, which serve as the energy factories of cells, are involved in cell differentiation,
calcium homeostasis, amino acid and fatty acid metabolism and apoptosis. In response to …

The induction of the mitochondrial unfolded protein response (UPR mt) results in increased
transcription of the gene encoding the mitochondrial chaperone HSP70. We systematically …

The pentatricopeptide repeat (PPR) family plays a major role in RNA stability, regulation,
processing, splicing, translation, and editing. Leucine-rich PPR-motif-containing protein …

Background Oxidative phosphorylation (OXPHOS) complexes consist of nuclear and
mitochondrial DNA-encoded subunits. Their biogenesis requires cross-compartment gene …

The disturbance in mitochondrial functions and homeostasis are the major features of
neuron degenerative conditions, like Parkinson's disease, Amyotrophic Lateral Sclerosis …

The mitochondrial matrix protease CLPP plays a central role in the activation of the
mitochondrial unfolded protein response (UPR mt) in Caenorhabditis elegans. Far less is …

Oxidative phosphorylation (OXPHOS) complexes, encoded by both mitochondrial and
nuclear DNA, are essential producers of cellular ATP, but how nuclear and mitochondrial …