Tumour-associated neutrophils in patients with cancer

ME Shaul, ZG Fridlender - Nature reviews Clinical oncology, 2019 - nature.com
The role and importance of neutrophils in cancer has become increasingly apparent over
the past decade. Neutrophils accumulate in the peripheral blood of patients with cancer …

IgA: structure, function, and developability

P de Sousa-Pereira, JM Woof - Antibodies, 2019 - mdpi.com
Immunoglobulin A (IgA) plays a key role in defending mucosal surfaces against attack by
infectious microorganisms. Such sites present a major site of susceptibility due to their vast …

Neutrophils in cancer: two sides of the same coin

E Uribe-Querol, C Rosales - Journal of immunology research, 2015 - Wiley Online Library
Neutrophils are the most abundant leukocytes in blood and are considered to be the first line
of defense during inflammation and infections. In addition, neutrophils are also found …

Control of phagocytosis by microbial pathogens

E Uribe-Querol, C Rosales - Frontiers in immunology, 2017 - frontiersin.org
Phagocytosis is a fundamental process of cells to capture and ingest foreign particles. Small
unicellular organisms such as free-living amoeba use this process to acquire food. In …

IgA and FcαRI: pathological roles and therapeutic opportunities

A Breedveld, M Van Egmond - Frontiers in immunology, 2019 - frontiersin.org
Immunoglobulin A (IgA) is the most abundant antibody class present at mucosal surfaces.
The production of IgA exceeds the production of all other antibodies combined, supporting …

Nanotechnology for protein delivery: Overview and perspectives

M Yu, J Wu, J Shi, OC Farokhzad - Journal of controlled release, 2016 - Elsevier
Protein-based therapeutics have made a significant impact in the treatment of a variety of
important human diseases. However, given their intrinsically vulnerable structure and …

Fc‐fusion proteins: new developments and future perspectives

DM Czajkowsky, J Hu, Z Shao… - EMBO molecular medicine, 2012 - embopress.org
Since the first description in 1989 of CD4‐Fc‐fusion antagonists that inhibit human immune
deficiency virus entry into T cells, Fc‐fusion proteins have been intensely investigated for …

Cancer‐related circulating and tumor‐associated neutrophils–subtypes, sources and function

ME Shaul, ZG Fridlender - The FEBS journal, 2018 - Wiley Online Library
In recent years, the role of neutrophils in cancer biology has been a matter of increasing
interest. Many patients with advanced cancer show high levels of neutrophilia, tumor …

Structure and function relationships in IgA

JM Woof, MW Russell - Mucosal immunology, 2011 - nature.com
Immunoglobulin A (IgA) has a critical role in immune defense particularly at the mucosal
surfaces, and is equipped to do so by the unique structural attributes of its heavy chain and …

Neutrophils in cancer

LW Treffers, IH Hiemstra, TW Kuijpers… - Immunological …, 2016 - Wiley Online Library
Neutrophils play an important role in cancer. This does not only relate to the well‐
established prognostic value of the presence of neutrophils, either in the blood or in tumor …