Recent advances in polysaccharide-based self-healing hydrogels for biomedical applications

Y Yang, L Xu, J Wang, Q Meng, S Zhong, Y Gao… - Carbohydrate …, 2022 - Elsevier
Hydrogels are a class of polymer materials with three-dimensional networks structure, which
can absorb a large number of water and biological fluids. Natural polysaccharides are ideal …

The interplay of fibroblasts, the extracellular matrix, and inflammation in scar formation

L Moretti, J Stalfort, TH Barker, D Abebayehu - Journal of Biological …, 2022 - ASBMB
Various forms of fibrosis, comprising tissue thickening and scarring, are involved in 40% of
deaths across the world. Since the discovery of scarless functional healing in fetuses prior to …

Stiffness sensing by cells

PA Janmey, DA Fletcher… - Physiological …, 2020 - journals.physiology.org
Physical stimuli are essential for the function of eukaryotic cells, and changes in physical
signals are important elements in normal tissue development as well as in disease initiation …

Static and dynamic: evolving biomaterial mechanical properties to control cellular mechanotransduction

W Xie, X Wei, H Kang, H Jiang, Z Chu, Y Lin… - Advanced …, 2023 - Wiley Online Library
The extracellular matrix (ECM) is a highly dynamic system that constantly offers physical,
biological, and chemical signals to embraced cells. Increasing evidence suggests that …

Focal adhesion dynamics in cellular function and disease

YG Mishra, B Manavathi - Cellular signalling, 2021 - Elsevier
Acting as a bridge between the cytoskeleton of the cell and the extra cellular matrix (ECM),
the cell-ECM adhesions with integrins at their core, play a major role in cell signalling to …

Stem cell‐recruiting injectable microgels for repairing osteoarthritis

Y Lei, Y Wang, J Shen, Z Cai, Y Zeng… - Advanced Functional …, 2021 - Wiley Online Library
The differentiation potentials and viability of stem cells are often impaired during cell
isolation and delivery. Inspired by the phenomenon where islands can recruit seabirds for …

[HTML][HTML] Pay attention to membrane tension: Mechanobiology of the cell surface

E Sitarska, A Diz-Muñoz - Current opinion in cell biology, 2020 - Elsevier
The cell surface is a mechanobiological unit that encompasses the plasma membrane, its
interacting proteins, and the complex underlying cytoskeleton. Recently, attention has been …

Responsive hydrogels based on triggered click reactions for liver cancer

JQ Zhu, H Wu, ZL Li, XF Xu, H Xing… - Advanced …, 2022 - Wiley Online Library
Globally, liver cancer, which is one of the major cancers worldwide, has attracted the
growing attention of technological researchers for its high mortality and limited treatment …

[HTML][HTML] Traction force microscopy–Measuring the forces exerted by cells

M Lekka, K Gnanachandran, A Kubiak, T Zieliński… - Micron, 2021 - Elsevier
Cells generate mechanical forces (traction forces, TFs) while interacting with the
extracellular matrix or neighbouring cells. Forces are generated by both cells and …

Probing force in living cells with optical tweezers: from single-molecule mechanics to cell mechanotransduction

C Arbore, L Perego, M Sergides, M Capitanio - Biophysical reviews, 2019 - Springer
The invention of optical tweezers more than three decades ago has opened new avenues in
the study of the mechanical properties of biological molecules and cells. Quantitative force …