Parvoviruses, infecting vertebrates and invertebrates, are a family of single-stranded DNA
viruses with small, non-enveloped capsids with T= 1 icosahedral symmetry. A quarter of a …

Metagenomic Next Generation Sequencing (mNGS) allows the evaluation of complex
microbial communities, avoiding isolation and cultivation of each microbial species, and …

Parvoviridae, a diverse family of small single-stranded DNA viruses was established in
1975. It was divided into two subfamilies, Parvovirinae and Densovirinae, in 1993 to …

Background Wild birds may harbor and transmit viruses that are potentially pathogenic to
humans, domestic animals, and other wildlife. Results Using the viral metagenomic …

Macrophages are central to the pathogenesis of kidney disease and serve as an effective
therapeutic target for kidney injury and fibrosis. Among them, M2-type macrophages have …

Chapparvoviruses (ChPVs) comprise a divergent, recently identified group of parvoviruses
(family Parvoviridae), associated with nephropathy in immunocompromised laboratory mice …

There are several causes of chronic kidney disease, but all of these patients have renal
fibrosis. Although many studies have examined the pathogenesis of renal fibrosis, there are …

The Tasmanian devil is an endangered carnivorous marsupial threatened by devil facial
tumor disease (DFTD). While research on DFTD has been extensive, little is known about …

Tilapia is one of the most important economic and fastest-growing species in aquaculture
worldwide. In 2015, an epidemic associated with severe mortality occurred in adult tilapia in …

Ducks can shed and disseminate viruses and thus play a role in cross-species transmission.
In the current study, we detected and characterised various avian parvoviruses and …